Burkholderia pseudomallei K96243, BPSL1070 (parC)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
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Gene Ontology

Ontology Accession Term GO Evidence Evidence Ontology (ECO) Code Reference Comments
Molecular Function GO:0003918 DNA topoisomerase type II (ATP-hydrolyzing) activity
ISM
Inferred from Sequence Model
Term mapped from: InterPro:SSF56719
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Cellular Component GO:0005694 chromosome
ISM
Inferred from Sequence Model
Term mapped from: InterPro:MF_00936
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Biological Process GO:0006265 DNA topological change
ISM
Inferred from Sequence Model
Term mapped from: InterPro:cd00187
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Biological Process GO:0006259 DNA metabolic process
ISM
Inferred from Sequence Model
Term mapped from: InterPro:G3DSA:3.90.199.10
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Molecular Function GO:0005524 ATP binding
ISM
Inferred from Sequence Model
Term mapped from: InterPro:SSF56719
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Molecular Function GO:0003918 DNA topoisomerase type II (ATP-hydrolyzing) activity
ISM
Inferred from Sequence Model
Term mapped from: InterPro:SSF56719
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Biological Process GO:0006265 DNA topological change
ISM
Inferred from Sequence Model
Term mapped from: InterPro:cd00187
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Molecular Function GO:0005524 ATP binding
ISM
Inferred from Sequence Model
Term mapped from: InterPro:SSF56719
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Molecular Function GO:0003677 DNA binding
ISM
Inferred from Sequence Model
Term mapped from: InterPro:cd00187
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Biological Process GO:0006259 DNA metabolic process
ISM
Inferred from Sequence Model
Term mapped from: InterPro:G3DSA:3.90.199.10
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Cellular Component GO:0005694 chromosome
ISM
Inferred from Sequence Model
Term mapped from: InterPro:MF_00936
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Molecular Function GO:0003677 DNA binding
ISM
Inferred from Sequence Model
Term mapped from: InterPro:cd00187
 ECO:0000259
match to InterPro signature evidence used in automatic assertion

Functional Predictions from Interpro

Analysis Accession Description Interpro Accession Interpro Description Amino Acid Start Amino Acid Stop E-value
TIGRFAM TIGR01062 parC_Gneg: DNA topoisomerase IV, A subunit 20 756 1.5E-234
SMART SM00434 IPR002205 DNA topoisomerase, type IIA, subunit A/C-terminal 20 492 4.6E-221
CDD cd00187 TOP4c IPR002205 DNA topoisomerase, type IIA, subunit A/C-terminal 40 501 0.0
Gene3D G3DSA:3.90.199.10 IPR013758 DNA topoisomerase, type IIA, subunit A/ C-terminal, alpha-beta 41 514 2.4E-188
SUPERFAMILY SSF56719 IPR013760 DNA topoisomerase, type IIA-like domain superfamily 40 514 3.53E-150
Coils Coil 496 516 -
Gene3D G3DSA:3.30.1360.40 246 362 2.4E-188
Coils Coil 457 491 -
Gene3D G3DSA:1.10.268.10 IPR013757 Type IIA DNA topoisomerase subunit A, alpha-helical domain superfamily 400 485 2.4E-188
Gene3D G3DSA:2.120.10.90 IPR035516 DNA gyrase/topoisomerase IV, subunit A, C-terminal 527 756 1.0E-18
Hamap MF_00936 DNA topoisomerase 4 subunit A [parC]. IPR005742 DNA topoisomerase IV, subunit A, Gram-negative 13 768 33.259
Pfam PF00521 DNA gyrase/topoisomerase IV, subunit A IPR002205 DNA topoisomerase, type IIA, subunit A/C-terminal 41 498 5.6E-132
SUPERFAMILY SSF101904 IPR035516 DNA gyrase/topoisomerase IV, subunit A, C-terminal 529 758 2.88E-46

Search for additional functional domains at the NCBI CDD database website. Go to this protein's amino acid sequence and follow the link.