Burkholderia pseudomallei K96243, BPSL0543 (purU)

Gene Ontology

Ontology	Accession	Term	GO Evidence	Evidence Ontology (ECO) Code	Reference	Comments
Molecular Function	GO:0016742	hydroxymethyl-, formyl- and related transferase activity	ISM Inferred from Sequence Model Term mapped from: InterPro:PF00551	ECO:0000259 match to InterPro signature evidence used in automatic assertion
Molecular Function	GO:0008864	formyltetrahydrofolate deformylase activity	ISM Inferred from Sequence Model Term mapped from: InterPro:MF_01927	ECO:0000259 match to InterPro signature evidence used in automatic assertion
Biological Process	GO:0006189	'de novo' IMP biosynthetic process	ISM Inferred from Sequence Model Term mapped from: InterPro:MF_01927	ECO:0000259 match to InterPro signature evidence used in automatic assertion
Biological Process	GO:0009058	biosynthetic process	ISM Inferred from Sequence Model Term mapped from: InterPro:PF00551	ECO:0000259 match to InterPro signature evidence used in automatic assertion

Pathways

Database	Xref	Pathway	Version	Evidence	PMID
MetaCyc		purine nucleobases degradation II (anaerobic)	InterPro 5.36-75.0	ECO:0000259 match to InterPro signature evidence used in automatic assertion
KEGG (InterPro)	00670	One carbon pool by folate	InterPro 5.36-75.0	ECO:0000259 match to InterPro signature evidence used in automatic assertion
KEGG	bps00670	One carbon pool by folate	73.0+/03-31, Mar 15	ECO:0000249 sequence similarity evidence used in automatic assertion
KEGG	bps00630	Glyoxylate and dicarboxylate metabolism	73.0+/03-31, Mar 15	ECO:0000249 sequence similarity evidence used in automatic assertion
KEGG (InterPro)	00630	Glyoxylate and dicarboxylate metabolism	InterPro 5.36-75.0	ECO:0000259 match to InterPro signature evidence used in automatic assertion
MetaCyc		formaldehyde oxidation VII (THF pathway)	InterPro 5.36-75.0	ECO:0000259 match to InterPro signature evidence used in automatic assertion
KEGG (InterPro)	00970	Aminoacyl-tRNA biosynthesis	InterPro 5.36-75.0	ECO:0000259 match to InterPro signature evidence used in automatic assertion
MetaCyc		folate transformations I	InterPro 5.36-75.0	ECO:0000259 match to InterPro signature evidence used in automatic assertion

Functional Predictions from Interpro

Analysis	Accession	Description	Interpro Accession	Interpro Description	Amino Acid Start	Amino Acid Stop	E-value
PRINTS	PR01575	Formyltetrahydrofolate deformylase signature	IPR004810	Formyltetrahydrofolate deformylase	94	116	8.2E-55
PRINTS	PR01575	Formyltetrahydrofolate deformylase signature	IPR004810	Formyltetrahydrofolate deformylase	9	35	8.2E-55
PRINTS	PR01575	Formyltetrahydrofolate deformylase signature	IPR004810	Formyltetrahydrofolate deformylase	244	266	8.2E-55
ProSiteProfiles	PS51671	ACT domain profile.	IPR002912	ACT domain	8	98	10.203
PRINTS	PR01575	Formyltetrahydrofolate deformylase signature	IPR004810	Formyltetrahydrofolate deformylase	266	291	8.2E-55
CDD	cd08648	FMT_core_Formyl-FH4-Hydrolase_C	IPR041729	Formyltetrahydrofolate deformylase, C-terminal hydrolase domain	93	292	6.85919E-115
Gene3D	G3DSA:3.30.70.260				2	91	2.9E-30
PRINTS	PR01575	Formyltetrahydrofolate deformylase signature	IPR004810	Formyltetrahydrofolate deformylase	41	53	8.2E-55
Hamap	MF_01927	Formyltetrahydrofolate deformylase [purU].	IPR004810	Formyltetrahydrofolate deformylase	4	292	48.413
TIGRFAM	TIGR00655	PurU: formyltetrahydrofolate deformylase	IPR004810	Formyltetrahydrofolate deformylase	8	292	4.8E-101
PIRSF	PIRSF036480				4	293	1.9E-109
PRINTS	PR01575	Formyltetrahydrofolate deformylase signature	IPR004810	Formyltetrahydrofolate deformylase	116	143	8.2E-55
SUPERFAMILY	SSF55021				4	91	2.08E-16
Pfam	PF00551	Formyl transferase	IPR002376	Formyl transferase, N-terminal	94	273	4.2E-38
Gene3D	G3DSA:3.40.50.170				93	292	8.1E-72
SUPERFAMILY	SSF53328		IPR036477	Formyl transferase, N-terminal domain superfamily	94	293	6.8E-62
CDD	cd04875	ACT_F4HF-DF			8	84	6.04708E-26

Search for additional functional domains at the NCBI CDD database website. Go to this protein's amino acid sequence and follow the link.