Burkholderia cenocepacia AU 1054, BCEN_RS27310 (aroE)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown

Gene Ontology

Ontology Accession Term GO Evidence Evidence Ontology (ECO) Code Reference Comments
Molecular Function GO:0050661 NADP binding
ISM
Inferred from Sequence Model
Term mapped from: InterPro:TIGR00507
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Molecular Function GO:0004764 shikimate 3-dehydrogenase (NADP+) activity
ISM
Inferred from Sequence Model
Term mapped from: InterPro:TIGR00507
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Biological Process GO:0019632 shikimate metabolic process
ISM
Inferred from Sequence Model
Term mapped from: InterPro:TIGR00507
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Biological Process GO:0055114 oxidation-reduction process
ISM
Inferred from Sequence Model
Term mapped from: InterPro:TIGR00507
 ECO:0000259
match to InterPro signature evidence used in automatic assertion

Pathways

Database Xref Pathway Version Evidence PMID
MetaCyc chorismate biosynthesis from 3-dehydroquinate InterPro 5.36-75.0 ECO:0000259
match to InterPro signature evidence used in automatic assertion
KEGG (InterPro) 00400 Phenylalanine, tyrosine and tryptophan biosynthesis InterPro 5.36-75.0 ECO:0000259
match to InterPro signature evidence used in automatic assertion

Functional Predictions from Interpro

Analysis Accession Description Interpro Accession Interpro Description Amino Acid Start Amino Acid Stop E-value
TIGRFAM TIGR00507 aroE: shikimate dehydrogenase IPR011342 Shikimate dehydrogenase 4 272 9.1E-73
Pfam PF01488 Shikimate / quinate 5-dehydrogenase IPR006151 Quinate/shikimate 5-dehydrogenase/glutamyl-tRNA reductase 121 197 2.0E-8
Pfam PF18317 Shikimate 5'-dehydrogenase C-terminal domain IPR041121 SDH, C-terminal 243 270 1.7E-9
SUPERFAMILY SSF51735 IPR036291 NAD(P)-binding domain superfamily 105 271 1.57E-40
Hamap MF_00222 Shikimate dehydrogenase (NADP(+)) [aroE]. IPR022893 Shikimate dehydrogenase family 2 275 29.698
Gene3D G3DSA:3.40.50.720 119 242 2.9E-73
CDD cd01065 NAD_bind_Shikimate_DH 105 260 9.55836E-27
SUPERFAMILY SSF53223 2 103 1.78E-26
Gene3D G3DSA:3.40.50.10860 6 260 2.9E-73
Pfam PF08501 Shikimate dehydrogenase substrate binding domain IPR013708 Shikimate dehydrogenase substrate binding, N-terminal 7 91 1.3E-18

Search for additional functional domains at the NCBI CDD database website. Go to this protein's amino acid sequence and follow the link.