Burkholderia cenocepacia AU 1054, BCEN_RS11470
Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
Gene Ontology
| Ontology | Accession | Term | GO Evidence | Evidence Ontology (ECO) Code | Reference | Comments |
|---|---|---|---|---|---|---|
| Molecular Function | GO:0008270 | zinc ion binding |
Inferred from Sequence Model
Term mapped from: InterPro:PIRSF000381
|
ECO:0000259 match to InterPro signature evidence used in automatic assertion |
||
| Molecular Function | GO:0008705 | methionine synthase activity |
Inferred from Sequence Model
Term mapped from: InterPro:PIRSF000381
|
ECO:0000259 match to InterPro signature evidence used in automatic assertion |
||
| Molecular Function | GO:0046872 | metal ion binding |
Inferred from Sequence Model
Term mapped from: InterPro:SSF52242
|
ECO:0000259 match to InterPro signature evidence used in automatic assertion |
||
| Biological Process | GO:0042558 | pteridine-containing compound metabolic process |
Inferred from Sequence Model
Term mapped from: InterPro:PS50972
|
ECO:0000259 match to InterPro signature evidence used in automatic assertion |
||
| Biological Process | GO:0044237 | cellular metabolic process |
Inferred from Sequence Model
Term mapped from: InterPro:SSF51717
|
ECO:0000259 match to InterPro signature evidence used in automatic assertion |
||
| Molecular Function | GO:0031419 | cobalamin binding |
Inferred from Sequence Model
Term mapped from: InterPro:PIRSF000381
|
ECO:0000259 match to InterPro signature evidence used in automatic assertion |
||
| Biological Process | GO:0009086 | methionine biosynthetic process |
Inferred from Sequence Model
Term mapped from: InterPro:PIRSF000381
|
ECO:0000259 match to InterPro signature evidence used in automatic assertion |
Pathways
| Database | Xref | Pathway | Version | Evidence | PMID |
|---|---|---|---|---|---|
| KEGG (InterPro) | 00450 | Selenocompound metabolism | InterPro 5.36-75.0 |
ECO:0000259
match to InterPro signature evidence used in automatic assertion |
|
| MetaCyc | folate transformations I | InterPro 5.36-75.0 |
ECO:0000259
match to InterPro signature evidence used in automatic assertion |
||
| MetaCyc | L-methionine biosynthesis IV (archaea) | InterPro 5.36-75.0 |
ECO:0000259
match to InterPro signature evidence used in automatic assertion |
||
| KEGG (InterPro) | 00270 | Cysteine and methionine metabolism | InterPro 5.36-75.0 |
ECO:0000259
match to InterPro signature evidence used in automatic assertion |
|
| KEGG (InterPro) | 00670 | One carbon pool by folate | InterPro 5.36-75.0 |
ECO:0000259
match to InterPro signature evidence used in automatic assertion |
|
| MetaCyc | folate transformations II | InterPro 5.36-75.0 |
ECO:0000259
match to InterPro signature evidence used in automatic assertion |
Functional Predictions from Interpro
| Analysis | Accession | Description | Interpro Accession | Interpro Description | Amino Acid Start | Amino Acid Stop | E-value |
|---|---|---|---|---|---|---|---|
| SUPERFAMILY | SSF52242 | IPR036724 | Cobalamin-binding domain superfamily | 416 | 572 | 1.57E-42 | |
| TIGRFAM | TIGR02082 | metH: methionine synthase | IPR011822 | Cobalamin-dependent methionine synthase | 4 | 875 | 0.0 |
| ProSiteProfiles | PS50974 | AdoMet activation domain profile. | IPR004223 | Vitamin B12-dependent methionine synthase, activation domain | 574 | 905 | 83.181 |
| PIRSF | PIRSF000381 | IPR011822 | Cobalamin-dependent methionine synthase | 1 | 878 | 0.0 | |
| SUPERFAMILY | SSF56507 | IPR037010 | Vitamin B12-dependent methionine synthase, activation domain superfamily | 579 | 905 | 4.58E-122 | |
| Gene3D | G3DSA:1.10.1240.10 | IPR036594 | Methionine synthase domain | 312 | 404 | 8.4E-38 | |
| SUPERFAMILY | SSF51717 | IPR011005 | Dihydropteroate synthase-like | 22 | 296 | 4.19E-94 | |
| SMART | SM01018 | IPR003759 | Cobalamin (vitamin B12)-binding module, cap domain | 320 | 407 | 7.0E-42 | |
| SUPERFAMILY | SSF47644 | IPR036594 | Methionine synthase domain | 315 | 406 | 1.83E-26 | |
| ProSiteProfiles | PS51332 | B12-binding domain profile. | IPR006158 | Cobalamin (vitamin B12)-binding domain | 420 | 559 | 42.549 |
| Pfam | PF02310 | B12 binding domain | IPR006158 | Cobalamin (vitamin B12)-binding domain | 422 | 515 | 2.4E-16 |
| CDD | cd00740 | MeTr | 22 | 278 | 1.53372E-132 | ||
| Gene3D | G3DSA:3.40.50.280 | 417 | 573 | 1.8E-53 | |||
| Pfam | PF02965 | Vitamin B12 dependent methionine synthase, activation domain | IPR004223 | Vitamin B12-dependent methionine synthase, activation domain | 615 | 889 | 3.1E-121 |
| ProSiteProfiles | PS51337 | B12-binding N-terminal domain profile. | IPR003759 | Cobalamin (vitamin B12)-binding module, cap domain | 313 | 411 | 36.9 |
| Gene3D | G3DSA:3.10.196.10 | IPR037010 | Vitamin B12-dependent methionine synthase, activation domain superfamily | 585 | 905 | 3.7E-134 | |
| CDD | cd02069 | methionine_synthase_B12_BD | IPR033706 | Methionine synthase, B12-binding domain | 322 | 549 | 2.11812E-131 |
| ProSiteProfiles | PS50972 | Pterin-binding domain profile. | IPR000489 | Pterin-binding domain | 22 | 283 | 32.385 |
| Coils | Coil | 558 | 578 | - | |||
| Gene3D | G3DSA:3.20.20.20 | IPR011005 | Dihydropteroate synthase-like | 6 | 308 | 2.2E-134 | |
| Pfam | PF00809 | Pterin binding enzyme | IPR000489 | Pterin-binding domain | 26 | 264 | 2.6E-61 |
| Pfam | PF02607 | B12 binding domain | IPR003759 | Cobalamin (vitamin B12)-binding module, cap domain | 322 | 399 | 1.3E-24 |
| Gene3D | G3DSA:1.10.288.10 | 614 | 776 | 3.7E-134 |
Search for additional functional domains at the NCBI CDD database website. Go to this protein's amino acid sequence and follow the link.