Burkholderia cenocepacia AU 1054, BCEN_RS11320

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown

Gene Ontology

Ontology Accession Term GO Evidence Evidence Ontology (ECO) Code Reference Comments
Molecular Function GO:0003824 catalytic activity
ISM
Inferred from Sequence Model
Term mapped from: InterPro:G3DSA:3.20.20.70
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Molecular Function GO:0051536 iron-sulfur cluster binding
ISM
Inferred from Sequence Model
Term mapped from: InterPro:PF04055
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Molecular Function GO:0016992 lipoate synthase activity
ISM
Inferred from Sequence Model
Term mapped from: InterPro:PIRSF005963
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Biological Process GO:0009107 lipoate biosynthetic process
ISM
Inferred from Sequence Model
Term mapped from: InterPro:PIRSF005963
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Molecular Function GO:0051539 4 iron, 4 sulfur cluster binding
ISM
Inferred from Sequence Model
Term mapped from: InterPro:PIRSF005963
 ECO:0000259
match to InterPro signature evidence used in automatic assertion

Pathways

Database Xref Pathway Version Evidence PMID
MetaCyc lipoate biosynthesis and incorporation (yeast) InterPro 5.36-75.0 ECO:0000259
match to InterPro signature evidence used in automatic assertion
KEGG (InterPro) 00785 Lipoic acid metabolism InterPro 5.36-75.0 ECO:0000259
match to InterPro signature evidence used in automatic assertion
MetaCyc lipoate biosynthesis and incorporation III (Bacillus) InterPro 5.36-75.0 ECO:0000259
match to InterPro signature evidence used in automatic assertion

Functional Predictions from Interpro

Analysis Accession Description Interpro Accession Interpro Description Amino Acid Start Amino Acid Stop E-value
Hamap MF_00206 Lipoyl synthase [lipA]. IPR003698 Lipoyl synthase 45 330 154.902
SFLD SFLDG01058 lipoyl synthase like 42 324 0.0
Gene3D G3DSA:3.20.20.70 IPR013785 Aldolase-type TIM barrel 89 303 4.8E-21
PIRSF PIRSF005963 IPR003698 Lipoyl synthase 5 328 3.9E-132
SFLD SFLDF00271 lipoyl synthase IPR003698 Lipoyl synthase 42 324 0.0
Pfam PF16881 N-terminal domain of lipoyl synthase of Radical_SAM family IPR031691 Lipoyl synthase, N-terminal 41 82 3.6E-9
TIGRFAM TIGR00510 lipA: lipoyl synthase IPR003698 Lipoyl synthase 42 325 7.4E-131
Pfam PF04055 Radical SAM superfamily IPR007197 Radical SAM 100 260 6.4E-17
SUPERFAMILY SSF102114 60 325 9.03E-68
SMART SM00729 IPR006638 Elp3/MiaB/NifB 93 302 3.2E-18
CDD cd01335 Radical_SAM 103 295 3.59392E-10
MobiDBLite mobidb-lite consensus disorder prediction 1 23 -

Search for additional functional domains at the NCBI CDD database website. Go to this protein's amino acid sequence and follow the link.