Burkholderia cenocepacia AU 1054, BCEN_RS11205
Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
Gene Ontology
| Ontology | Accession | Term | GO Evidence | Evidence Ontology (ECO) Code | Reference | Comments |
|---|---|---|---|---|---|---|
| Biological Process | GO:0006750 | glutathione biosynthetic process |
Inferred from Sequence Model
Term mapped from: InterPro:PF02951
|
ECO:0000259 match to InterPro signature evidence used in automatic assertion |
||
| Molecular Function | GO:0005524 | ATP binding |
Inferred from Sequence Model
Term mapped from: InterPro:G3DSA:3.30.1490.20
|
ECO:0000259 match to InterPro signature evidence used in automatic assertion |
||
| Molecular Function | GO:0046872 | metal ion binding |
Inferred from Sequence Model
Term mapped from: InterPro:PS50975
|
ECO:0000259 match to InterPro signature evidence used in automatic assertion |
||
| Molecular Function | GO:0004363 | glutathione synthase activity |
Inferred from Sequence Model
Term mapped from: InterPro:PF02951
|
ECO:0000259 match to InterPro signature evidence used in automatic assertion |
Pathways
| Database | Xref | Pathway | Version | Evidence | PMID |
|---|---|---|---|---|---|
| KEGG (InterPro) | 00270 | Cysteine and methionine metabolism | InterPro 5.36-75.0 |
ECO:0000259
match to InterPro signature evidence used in automatic assertion |
|
| MetaCyc | ophthalmate biosynthesis | InterPro 5.36-75.0 |
ECO:0000259
match to InterPro signature evidence used in automatic assertion |
||
| KEGG (InterPro) | 00480 | Glutathione metabolism | InterPro 5.36-75.0 |
ECO:0000259
match to InterPro signature evidence used in automatic assertion |
Functional Predictions from Interpro
| Analysis | Accession | Description | Interpro Accession | Interpro Description | Amino Acid Start | Amino Acid Stop | E-value |
|---|---|---|---|---|---|---|---|
| Pfam | PF02955 | Prokaryotic glutathione synthetase, ATP-grasp domain | IPR004218 | Prokaryotic glutathione synthetase, ATP-binding | 128 | 301 | 6.4E-72 |
| Pfam | PF02951 | Prokaryotic glutathione synthetase, N-terminal domain | IPR004215 | Prokaryotic glutathione synthetase, N-terminal | 1 | 124 | 3.0E-39 |
| ProSiteProfiles | PS50975 | ATP-grasp fold profile. | IPR011761 | ATP-grasp fold | 129 | 314 | 25.076 |
| SUPERFAMILY | SSF52440 | IPR016185 | Pre-ATP-grasp domain superfamily | 1 | 126 | 4.32E-37 | |
| Hamap | MF_00162 | Glutathione synthetase [gshB]. | IPR006284 | Glutathione synthetase, prokaryotic | 1 | 318 | 159.447 |
| SUPERFAMILY | SSF56059 | 128 | 315 | 2.7E-57 | |||
| Gene3D | G3DSA:3.30.470.20 | 119 | 298 | 4.6E-99 | |||
| Gene3D | G3DSA:3.40.50.20 | 6 | 118 | 4.6E-99 | |||
| TIGRFAM | TIGR01380 | glut_syn: glutathione synthase | IPR006284 | Glutathione synthetase, prokaryotic | 1 | 316 | 1.3E-120 |
| Gene3D | G3DSA:3.30.1490.20 | IPR013815 | ATP-grasp fold, subdomain 1 | 141 | 205 | 4.6E-99 |
Search for additional functional domains at the NCBI CDD database website. Go to this protein's amino acid sequence and follow the link.