Burkholderia cenocepacia AU 1054, BCEN_RS10570
Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
Gene Ontology
| Ontology | Accession | Term | GO Evidence | Evidence Ontology (ECO) Code | Reference | Comments |
|---|---|---|---|---|---|---|
| Molecular Function | GO:0030170 | pyridoxal phosphate binding |
Inferred from Sequence Model
Term mapped from: InterPro:PS00165
|
ECO:0000259 match to InterPro signature evidence used in automatic assertion |
||
| Biological Process | GO:0006520 | cellular amino acid metabolic process |
Inferred from Sequence Model
Term mapped from: InterPro:PS00165
|
ECO:0000259 match to InterPro signature evidence used in automatic assertion |
||
| Molecular Function | GO:0004794 | L-threonine ammonia-lyase activity |
Inferred from Sequence Model
Term mapped from: InterPro:TIGR01124
|
ECO:0000259 match to InterPro signature evidence used in automatic assertion |
||
| Biological Process | GO:0009097 | isoleucine biosynthetic process |
Inferred from Sequence Model
Term mapped from: InterPro:TIGR01124
|
ECO:0000259 match to InterPro signature evidence used in automatic assertion |
Pathways
| Database | Xref | Pathway | Version | Evidence | PMID |
|---|---|---|---|---|---|
| KEGG (InterPro) | 00260 | Glycine, serine and threonine metabolism | InterPro 5.36-75.0 |
ECO:0000259
match to InterPro signature evidence used in automatic assertion |
|
| KEGG (InterPro) | 00290 | Valine, leucine and isoleucine biosynthesis | InterPro 5.36-75.0 |
ECO:0000259
match to InterPro signature evidence used in automatic assertion |
Functional Predictions from Interpro
| Analysis | Accession | Description | Interpro Accession | Interpro Description | Amino Acid Start | Amino Acid Stop | E-value |
|---|---|---|---|---|---|---|---|
| Gene3D | G3DSA:3.40.50.1100 | 51 | 150 | 3.8E-135 | |||
| Gene3D | G3DSA:3.40.1020.10 | IPR038110 | Threonine dehydratase, ACT-like domain superfamily | 332 | 507 | 5.0E-75 | |
| CDD | cd04906 | ACT_ThrD-I_1 | 332 | 415 | 2.42231E-44 | ||
| ProSiteProfiles | PS51672 | ACT-like domain profile. | IPR001721 | Threonine dehydratase, ACT-like domain | 427 | 498 | 17.613 |
| Pfam | PF00291 | Pyridoxal-phosphate dependent enzyme | IPR001926 | Pyridoxal-phosphate dependent enzyme | 19 | 310 | 4.5E-79 |
| Pfam | PF00585 | C-terminal regulatory domain of Threonine dehydratase | IPR001721 | Threonine dehydratase, ACT-like domain | 323 | 412 | 7.1E-31 |
| ProSitePatterns | PS00165 | Serine/threonine dehydratases pyridoxal-phosphate attachment site. | IPR000634 | Serine/threonine dehydratase, pyridoxal-phosphate-binding site | 43 | 56 | - |
| SUPERFAMILY | SSF55021 | 413 | 506 | 5.49E-27 | |||
| CDD | cd01562 | Thr-dehyd | 7 | 314 | 2.93533E-152 | ||
| SUPERFAMILY | SSF53686 | IPR036052 | Tryptophan synthase beta subunit-like PLP-dependent enzyme | 5 | 360 | 3.01E-97 | |
| CDD | cd04907 | ACT_ThrD-I_2 | 426 | 506 | 1.51114E-45 | ||
| Gene3D | G3DSA:3.40.50.1100 | 16 | 321 | 3.8E-135 | |||
| TIGRFAM | TIGR01124 | ilvA_2Cterm: threonine ammonia-lyase, biosynthetic | IPR005787 | Threonine dehydratase, biosynthetic | 5 | 506 | 7.0E-249 |
| ProSiteProfiles | PS51672 | ACT-like domain profile. | IPR001721 | Threonine dehydratase, ACT-like domain | 333 | 404 | 14.23 |
| Pfam | PF00585 | C-terminal regulatory domain of Threonine dehydratase | IPR001721 | Threonine dehydratase, ACT-like domain | 424 | 506 | 5.8E-24 |
Search for additional functional domains at the NCBI CDD database website. Go to this protein's amino acid sequence and follow the link.