Burkholderia cenocepacia AU 1054, BCEN_RS10360

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown

Gene Ontology

Ontology Accession Term GO Evidence Evidence Ontology (ECO) Code Reference Comments
Molecular Function GO:0016740 transferase activity
ISM
Inferred from Sequence Model
Term mapped from: InterPro:TIGR00089
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Molecular Function GO:0051539 4 iron, 4 sulfur cluster binding
ISM
Inferred from Sequence Model
Term mapped from: InterPro:TIGR00089
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Molecular Function GO:0051536 iron-sulfur cluster binding
ISM
Inferred from Sequence Model
Term mapped from: InterPro:SFLDS00029
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Biological Process GO:0006400 tRNA modification
ISM
Inferred from Sequence Model
Term mapped from: InterPro:TIGR00089
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Molecular Function GO:0035596 methylthiotransferase activity
ISM
Inferred from Sequence Model
Term mapped from: InterPro:PS51449
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Molecular Function GO:0003824 catalytic activity
ISM
Inferred from Sequence Model
Term mapped from: InterPro:SFLDS00029
 ECO:0000259
match to InterPro signature evidence used in automatic assertion

Functional Predictions from Interpro

Analysis Accession Description Interpro Accession Interpro Description Amino Acid Start Amino Acid Stop E-value
SFLD SFLDS00029 Radical SAM IPR007197 Radical SAM 2 446 0.0
SMART SM00729 IPR006638 Elp3/MiaB/NifB 147 369 1.2E-58
SFLD SFLDF00273 (dimethylallyl)adenosine tRNA methylthiotransferase (MiaB-like) IPR006463 tRNA-2-methylthio-N(6)-dimethylallyladenosine synthase MiaB 2 446 0.0
SFLD SFLDG01082 B12-binding domain containing 32 360 6.5E-35
Gene3D G3DSA:3.80.30.20 IPR023404 Radical SAM, alpha/beta horseshoe 145 382 1.8E-82
TIGRFAM TIGR00089 TIGR00089: radical SAM methylthiotransferase, MiaB/RimO family IPR005839 Methylthiotransferase 4 443 3.5E-147
TIGRFAM TIGR01574 miaB-methiolase: tRNA-i(6)A37 thiotransferase enzyme MiaB 4 446 3.6E-176
Gene3D G3DSA:3.40.50.12160 IPR038135 Methylthiotransferase, N-terminal domain superfamily 3 136 6.4E-33
Pfam PF00919 Uncharacterized protein family UPF0004 IPR013848 Methylthiotransferase, N-terminal 4 104 2.1E-29
Pfam PF01938 TRAM domain IPR002792 TRAM domain 380 446 4.0E-16
SUPERFAMILY SSF102114 129 373 1.96E-60
ProSitePatterns PS01278 Methylthiotransferase radical SAM domain signature. IPR020612 Methylthiotransferase, conserved site 151 171 -
Pfam PF04055 Radical SAM superfamily IPR007197 Radical SAM 151 326 3.5E-29
Hamap MF_01864 tRNA-2-methylthio-N(6)-dimethylallyladenosine synthase [miaB]. IPR006463 tRNA-2-methylthio-N(6)-dimethylallyladenosine synthase MiaB 3 447 75.57
CDD cd01335 Radical_SAM 156 358 3.55567E-9
ProSiteProfiles PS51449 Methylthiotransferase N-terminal domain profile. IPR013848 Methylthiotransferase, N-terminal 3 120 37.884
ProSiteProfiles PS50926 TRAM domain profile. IPR002792 TRAM domain 380 447 17.351

Search for additional functional domains at the NCBI CDD database website. Go to this protein's amino acid sequence and follow the link.