Burkholderia cenocepacia J2315, BCAM0188 (cepR2)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
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Gene Feature Overview

Strain Burkholderia cenocepacia J2315
Locus Tag
BCAM0188
NCBI Locus TagQU43_RS55360
Name
cepR2
Replicon chromosome 2
Genomic location 219739 - 220452 (- strand)

Cross-References

RefSeq WP_006490829.1
GI 206562058
Entrez 6927984
GI 206562058
INSDC CAR54046.1
NCBI Locus Tag QU43_RS55360
NCBI Old Locus Tag BCAM0188
RefSeq WP_006490829.1,GeneID
UniParc UPI00017B9D31
UniProtKB Acc B4EHM0
UniProtKB ID B4EHM0_BURCJ
UniRef100 UniRef100_B4EHM0
UniRef50 UniRef50_G7H9N0
UniRef90 UniRef90_G7H9N0

Product

Feature Type CDS
Coding Frame 1
Product Name
CepR2
Product Name Confidence: Class 1
Synonyms CepR2
Evidence for Translation
Charge (pH 7) 3.03
Kyte-Doolittle Hydrophobicity Value -0.023
Molecular Weight (kDa) 26093.8
Isoelectric Point (pI) 8.01

Subcellular localization

Individual Mappings
Localization Confidence PMID
Cytoplasmic Class 3
Unknown Class 3
Additional evidence for subcellular localization

PDB 3D Structures

Accession Header Accession Date Compound Source Resolution Method Percent Identity
5L10 TRANSCRIPTION 07/28/16 Crystal Structure of N-Acylhomoserine Lactone Dependent LuxR Family Transcriptionl Factor CepR2 from Burkholderia cenocepacia BURKHOLDERIA CENOCEPACIA (STRAIN ATCC BAA-245 / DSM 16553 / LMG 16656 / NCTC 13227 / J2315 / CF5610) 2.75 X-RAY DIFFRACTION 100.0

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 183 genera

Orthologs/Comparative Genomics

Burkholderia Ortholog Group BG003718 (1367 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: BCAM0188
Search term: cepR2
Search term: CepR2

References

A Burkholderia cenocepacia orphan LuxR homolog is involved in quorum-sensing regulation.
Malott RJ, O'Grady EP, Toller J, Inhulsen S, Eberl L, Sokol PA.
J Bacteriol. 2009 Apr;191(8):2447-60.
PubMed ID: 19201791
PubMed ID: 28614901