Burkholderia cenocepacia J2315, BCAL0343 (bcsL)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
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Gene Feature Overview

Strain Burkholderia cenocepacia J2315
Locus Tag
BCAL0343
NCBI Locus TagQU43_RS38250
Name
bcsL
Synonym: bcsLB
Replicon chromosome 1
Genomic location 368997 - 369500 (+ strand)

Cross-References

RefSeq WP_006477093.1
GI 206558749
Entrez 6930888
GI 206558749
INSDC CAR50653.1
NCBI Locus Tag QU43_RS38250
NCBI Old Locus Tag BCAL0343
RefSeq WP_006477093.1,GeneID
UniParc UPI00003010A6
UniProtKB Acc B4E6R5
UniProtKB ID B4E6R5_BURCJ
UniRef100 UniRef100_B1JUN9
UniRef50 UniRef50_D8N062
UniRef90 UniRef90_I1WF16

Product

Feature Type CDS
Coding Frame 1
Product Name
BcsL
Evidence for Translation
Charge (pH 7) 0.88
Kyte-Doolittle Hydrophobicity Value -0.526
Molecular Weight (kDa) 18422.6
Isoelectric Point (pI) 7.29

Subcellular localization

Individual Mappings
Localization Confidence PMID
Extracellular Class 3
Additional evidence for subcellular localization

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 69 genera

Orthologs/Comparative Genomics

Burkholderia Ortholog Group BG000368 (661 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: BCAL0343
Search term: bcsL
Search term: BcsL

References

BcsKC is an essential protein for the type VI secretion system activity in Burkholderia cenocepacia that forms an outer membrane complex with BcsLB.
Aubert D, MacDonald DK, Valvano MA.
J Biol Chem. 2010 Nov 12;285(46):35988-98.
PubMed ID: 20729192