Burkholderia pseudomallei K96243, BPSL1105 (bspR)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
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Gene Feature Overview

Strain Burkholderia pseudomallei K96243 - Assembly GCF_000011545.1
Locus Tag
BPSL1105
Name
bspR
Replicon chromosome 1
Genomic location 1275668 - 1276300 (+ strand)
CommentThe T3SS3 and T6SS1 genes are coordinately and hierarchically regulated by BspR (PMID:20345664)

Cross-References

RefSeq YP_107726.1
GI 53718740
Entrez 3093813
GI 53718740
INSDC CAH35098.1
NCBI Locus Tag BPSL1105
RefSeq YP_107726.1,GeneID
UniParc UPI000043AE94
UniProtKB Acc Q63VZ0
UniProtKB ID Q63VZ0_BURPS
UniRef100 UniRef100_D7SD96
UniRef50 UniRef50_G8M6P6
UniRef90 UniRef90_D7SD96

Product

Feature Type CDS
Coding Frame 1
Product Name
bsa-specific regulator BspR
Product Name Confidence: Class 1
Synonyms TetR family regulatory protein
Evidence for Translation
Charge (pH 7) 2.96
Kyte-Doolittle Hydrophobicity Value -0.247
Molecular Weight (kDa) 24321.7
Isoelectric Point (pI) 9.17

Subcellular localization

Individual Mappings
Localization Confidence PMID
Cytoplasmic Class 3
Additional evidence for subcellular localization

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 275 genera

Orthologs/Comparative Genomics

Burkholderia Ortholog Group BG002209 (653 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: BPSL1105
Search term: bspR

References

Identification of a regulatory cascade controlling Type III Secretion System 3 gene expression in Burkholderia pseudomallei.
Sun GW(1), Chen Y, Liu Y, Tan GY, Ong C, Tan P, Gan YH.
Mol Microbiol. 2010 May;76(3):677-89.
PubMed ID: 20345664
Characterization and analysis of the Burkholderia pseudomallei BsaN virulence regulon.
Chen Y, Schröder I, French CT, Jaroszewicz A, Yee XJ, Teh BE, Toesca IJ, Miller JF, Gan YH(1).
BMC Microbiol. 2014 Aug 1;14:206.
PubMed ID: 25085508