Burkholderia cenocepacia J2315, BCAS0381 (gabD)

Gene Feature Overview

Strain	Burkholderia cenocepacia J2315 GCF_000009485.1|latest
Locus Tag	BCAS0381
NCBI Locus Tag	QU43_RS70580
Name	gabD
Replicon	chromosome 3
Genomic location	446246 - 447718 (- strand)

Cross-References

RefSeq	WP_006493468.1
GI	197295230
Entrez	6804271
GI	197295230
INSDC	CAR57313.1
NCBI Locus Tag	QU43_RS70580
NCBI Old Locus Tag	BCAS0381
RefSeq	WP_006493468.1,GeneID
UniParc	UPI00017BB17E
UniProtKB Acc	B4END1
UniProtKB ID	B4END1_BURCJ
UniRef100	UniRef100_B4END1
UniRef50	UniRef50_P51650-2
UniRef90	UniRef90_B4END1

Product

Feature Type	CDS
Coding Frame	1
Product Name	succinate-semialdehyde dehydrogenase (NADP+)
Synonyms
Evidence for Translation
Charge (pH 7)	-1.14
Kyte-Doolittle Hydrophobicity Value	0.048
Molecular Weight (kDa)	51624.2
Isoelectric Point (pI)	6.55

Subcellular localization

Individual Mappings	Localization Confidence PMID Cytoplasmic Class 3 20472543
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

Pathogen Association Analysis

Results

Common Found in both pathogen and nonpathogenic strains Hits to this gene were found in 605 genera

Orthologs/Comparative Genomics

Burkholderia Ortholog Group	BG005393 (292 members)
Putative Inparalogs	None Found

Interactions

STRING database

Search for predicted protein-protein interactions using: Search term: BCAS0381 Search term: gabD Search term: succinate-semialdehyde dehydrogenase (NADP+)

Human Homologs

Ensembl 97, assembly GRCh38.p12

ENSP00000350191 aldehyde dehydrogenase 5 family member A1 [Source:HGNC Symbol;Acc:HGNC:408] E-value: 3.0e-130 Percent Identity: 50.5

References