Burkholderia cenocepacia J2315, BCAM1478 (tyrB)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse

Gene Feature Overview

Strain Burkholderia cenocepacia J2315
GCF_000009485.1|latest
Locus Tag
BCAM1478
NCBI Locus TagQU43_RS61740
Name
tyrB
Replicon chromosome 2
Genomic location 1643715 - 1644917 (+ strand)

Cross-References

RefSeq WP_006481706.1
GI 206563328
Entrez 6930355
GI 206563328
INSDC CAR55333.1
NCBI Locus Tag QU43_RS61740
NCBI Old Locus Tag BCAM1478
RefSeq WP_006481706.1,GeneID
UniParc UPI00017B9EE1
UniProtKB Acc B4EJ31
UniProtKB ID B4EJ31_BURCJ
UniRef100 UniRef100_B4EJ31
UniRef50 UniRef50_O85746
UniRef90 UniRef90_B4EJ31

Product

Feature Type CDS
Coding Frame 1
Product Name
aromatic amino acid aminotransferase
Synonyms
Evidence for Translation
Charge (pH 7) -4.22
Kyte-Doolittle Hydrophobicity Value -0.102
Molecular Weight (kDa) 43579.1
Isoelectric Point (pI) 6.12

Subcellular localization

Individual Mappings
Localization Confidence PMID
Cytoplasmic Class 3
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

PDB 3D Structures

Accession Header Accession Date Compound Source Resolution Method Percent Identity
4WD2 TRANSFERASE 09/06/14 Crystal structure of an aromatic amino acid aminotransferase from Burkholderia cenocepacia J2315 BURKHOLDERIA CENOCEPACIA K56-2VALVANO 1.95 X-RAY DIFFRACTION 100.0

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 185 genera

Orthologs/Comparative Genomics

Burkholderia Ortholog Group BG003425 (651 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: BCAM1478
Search term: tyrB

Human Homologs

Ensembl 97, assembly GRCh38.p12
glutamic-oxaloacetic transaminase 2 [Source:HGNC Symbol;Acc:HGNC:4433]
E-value: 1.7e-88
Percent Identity: 42.7

References

No references are associated with this feature.