Burkholderia cenocepacia J2315, BCAM0463 (metC)

Gene Feature Overview

Strain	Burkholderia cenocepacia J2315 GCF_000009485.1|latest
Locus Tag	BCAM0463
NCBI Locus Tag	QU43_RS56705
Name	metC
Replicon	chromosome 2
Genomic location	516957 - 518120 (- strand)

Cross-References

RefSeq	WP_006484553.1
GI	206562323
Entrez	6928239
GI	206562323
INSDC	CAR54320.1
NCBI Locus Tag	QU43_RS56705
NCBI Old Locus Tag	BCAM0463
RefSeq	WP_006484553.1,GeneID
UniParc	UPI00017B9D00
UniProtKB Acc	B4EJW5
UniProtKB ID	B4EJW5_BURCJ
UniRef100	UniRef100_A0A095F8R1
UniRef50	UniRef50_A0A095F8R1
UniRef90	UniRef90_A0A095F8R1

Product

Feature Type	CDS
Coding Frame	1
Product Name	putative cystathionine beta-lyase
Synonyms
Evidence for Translation
Charge (pH 7)	-7.74
Kyte-Doolittle Hydrophobicity Value	0.053
Molecular Weight (kDa)	42197.9
Isoelectric Point (pI)	5.58

Subcellular localization

Individual Mappings	Localization Confidence PMID Cytoplasmic Class 3 20472543
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

Pathogen Association Analysis

Results

Common Found in both pathogen and nonpathogenic strains Hits to this gene were found in 567 genera

Orthologs/Comparative Genomics

Burkholderia Ortholog Group	BG003818 (111 members)
Putative Inparalogs	None Found

Interactions

STRING database

Search for predicted protein-protein interactions using: Search term: BCAM0463 Search term: metC Search term: putative cystathionine beta-lyase

Human Homologs

Ensembl 97, assembly GRCh38.p12

ENSP00000359976 cystathionine gamma-lyase [Source:HGNC Symbol;Acc:HGNC:2501] E-value: 2.3e-45 Percent Identity: 31.9

References