Burkholderia cenocepacia J2315, BCAL3421 (accC)

Gene Feature Overview

Strain	Burkholderia cenocepacia J2315 GCF_000009485.1|latest
Locus Tag	BCAL3421
NCBI Locus Tag	QU43_RS53805
Name	accC
Replicon	chromosome 1
Genomic location	3746507 - 3747874 (+ strand)

Cross-References

RefSeq	WP_006490723.1
GI	206561758
Entrez	6933271
GI	206561758
INSDC	CAR53744.1
NCBI Locus Tag	QU43_RS53805
NCBI Old Locus Tag	BCAL3421
RefSeq	WP_006490723.1,GeneID
UniParc	UPI00017B9709
UniProtKB Acc	B4E5V1
UniProtKB ID	B4E5V1_BURCJ
UniRef100	UniRef100_B4E5V1
UniRef50	UniRef50_P43873
UniRef90	UniRef90_Q2SZE0

Product

Feature Type	CDS
Coding Frame	1
Product Name	acetyl-CoA carboxylase biotin carboxylase subunit
Synonyms
Evidence for Translation
Charge (pH 7)	-1.79
Kyte-Doolittle Hydrophobicity Value	-0.272
Molecular Weight (kDa)	50534.5
Isoelectric Point (pI)	6.68

Subcellular localization

Individual Mappings	Localization Confidence PMID Cytoplasmic Class 3 20472543
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

Pathogen Association Analysis

Results

Common Found in both pathogen and nonpathogenic strains Hits to this gene were found in 622 genera

Orthologs/Comparative Genomics

Burkholderia Ortholog Group	BG000491 (654 members)
Putative Inparalogs	None Found

Interactions

STRING database

Search for predicted protein-protein interactions using: Search term: BCAL3421 Search term: accC Search term: acetyl-CoA carboxylase biotin carboxylase subunit

Human Homologs

Ensembl 97, assembly GRCh38.p12	ENSP00000365463 propionyl-CoA carboxylase subunit alpha [Source:HGNC Symbol;Acc:HGNC:8653] E-value: 3.4e-120 Percent Identity: 48.5
Ensembl 97, assembly GRCh38.p12	ENSP00000365462 propionyl-CoA carboxylase subunit alpha [Source:HGNC Symbol;Acc:HGNC:8653] E-value: 3.4e-120 Percent Identity: 48.5
Ensembl 97, assembly GRCh38.p12	ENSP00000365456 propionyl-CoA carboxylase subunit alpha [Source:HGNC Symbol;Acc:HGNC:8653] E-value: 3.4e-120 Percent Identity: 48.5

References