Burkholderia cenocepacia J2315, BCAL1873 (purA)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse

Gene Feature Overview

Strain Burkholderia cenocepacia J2315
GCF_000009485.1|latest
Locus Tag
BCAL1873
NCBI Locus TagQU43_RS45910
Name
purA
Replicon chromosome 1
Genomic location 2068145 - 2069491 (- strand)

Cross-References

RefSeq WP_006485901.1
GI 206560236
Entrez 6932089
GI 206560236
INSDC CAR52173.1
NCBI Locus Tag QU43_RS45910
NCBI Old Locus Tag BCAL1873
RefSeq WP_006485901.1,GeneID
UniParc UPI00017B956C
UniProtKB Acc B4EAH2
UniProtKB ID B4EAH2_BURCJ
UniRef100 UniRef100_B4EAH2
UniRef50 UniRef50_P45283
UniRef90 UniRef90_Q2SWD3

Product

Feature Type CDS
Coding Frame 1
Product Name
adenylosuccinate synthetase
Synonyms
Evidence for Translation
Charge (pH 7) -1.49
Kyte-Doolittle Hydrophobicity Value -0.116
Molecular Weight (kDa) 48234.5
Isoelectric Point (pI) 6.63

Subcellular localization

Individual Mappings
Localization Confidence PMID
Cytoplasmic Class 3
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

PDB 3D Structures

Accession Header Accession Date Compound Source Resolution Method Percent Identity
3UE9 LIGASE 10/28/11 Crystal structure of Adenylosuccinate synthetase (AMPSase) (purA) from Burkholderia thailandensis BURKHOLDERIA THAILANDENSIS 1.95 X-RAY DIFFRACTION 93.8

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 640 genera

Orthologs/Comparative Genomics

Burkholderia Ortholog Group BG001638 (652 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: BCAL1873
Search term: purA

Human Homologs

Ensembl 97, assembly GRCh38.p12
adenylosuccinate synthase like 1 [Source:HGNC Symbol;Acc:HGNC:20093]
E-value: 7.2e-91
Percent Identity: 41.4

References

No references are associated with this feature.