Burkholderia cenocepacia J2315, BCAL1803 (tkrA)

Gene Feature Overview

Strain	Burkholderia cenocepacia J2315 GCF_000009485.1|latest
Locus Tag	BCAL1803
NCBI Locus Tag	QU43_RS45550
Name	tkrA
Replicon	chromosome 1
Genomic location	1988431 - 1989396 (- strand)

Cross-References

RefSeq	WP_006491176.1
GI	206560165
Entrez	6932029
GI	206560165
INSDC	CAR52102.1
NCBI Locus Tag	QU43_RS45550
NCBI Old Locus Tag	BCAL1803
RefSeq	WP_006491176.1,GeneID
UniParc	UPI00017B9459
UniProtKB Acc	B4E9Y4
UniProtKB ID	B4E9Y4_BURCJ
UniRef100	UniRef100_B4E9Y4
UniRef50	UniRef50_A0A071MGY8
UniRef90	UniRef90_A0A071MGY8

Product

Feature Type	CDS
Coding Frame	1
Product Name	2-ketogluconate reductase
Synonyms
Evidence for Translation
Charge (pH 7)	0.07
Kyte-Doolittle Hydrophobicity Value	0.098
Molecular Weight (kDa)	34029.6
Isoelectric Point (pI)	7.02

Subcellular localization

Individual Mappings	Localization Confidence PMID Cytoplasmic Class 3 20472543
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

Pathogen Association Analysis

Results

Common Found in both pathogen and nonpathogenic strains Hits to this gene were found in 641 genera

Orthologs/Comparative Genomics

Burkholderia Ortholog Group	BG001561 (630 members)
Putative Inparalogs	None Found

Interactions

STRING database

Search for predicted protein-protein interactions using: Search term: BCAL1803 Search term: tkrA Search term: 2-ketogluconate reductase

Human Homologs

Ensembl 97, assembly GRCh38.p12

ENSP00000313432 glyoxylate and hydroxypyruvate reductase [Source:HGNC Symbol;Acc:HGNC:4570] E-value: 9.8e-50 Percent Identity: 45.1

References