Burkholderia cenocepacia J2315, BCAL1215 (lpdV)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse

Gene Feature Overview

Strain Burkholderia cenocepacia J2315
GCF_000009485.1|latest
Locus Tag
BCAL1215
NCBI Locus TagQU43_RS42570
Name
lpdV
Replicon chromosome 1
Genomic location 1325076 - 1326467 (+ strand)

Cross-References

RefSeq WP_006481751.1
GI 206559592
Entrez 6933416
GI 206559592
INSDC CAR51517.1
NCBI Locus Tag QU43_RS42570
NCBI Old Locus Tag BCAL1215
RefSeq WP_006481751.1,GeneID
UniParc UPI00017B93BA
UniProtKB Acc B4EEF2
UniProtKB ID B4EEF2_BURCJ
UniRef100 UniRef100_B4EEF2
UniRef50 UniRef50_P09063
UniRef90 UniRef90_B4EEF2

Product

Feature Type CDS
Coding Frame 1
Product Name
dihydrolipoamide dehydrogenase
Synonyms
Evidence for Translation
Charge (pH 7) 1.65
Kyte-Doolittle Hydrophobicity Value 0.202
Molecular Weight (kDa) 48621.7
Isoelectric Point (pI) 7.25

Subcellular localization

Individual Mappings
Localization Confidence PMID
Cytoplasmic Class 3
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

PDB 3D Structures

Accession Header Accession Date Compound Source Resolution Method Percent Identity
6CMZ OXIDOREDUCTASE 03/06/18 2.3 Angstrom Resolution Crystal Structure of Dihydrolipoamide Dehydrogenase from Burkholderia cenocepacia in Complex with FAD and NAD BURKHOLDERIA CENOCEPACIA (STRAIN ATCC BAA-245 / DSM 16553 / LMG 16656 / NCTC 13227 / J2315 / CF5610) 2.3 X-RAY DIFFRACTION 100.0

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 650 genera

Orthologs/Comparative Genomics

Burkholderia Ortholog Group BG001086 (576 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: BCAL1215
Search term: lpdV

Human Homologs

Ensembl 97, assembly GRCh38.p12
dihydrolipoamide dehydrogenase [Source:HGNC Symbol;Acc:HGNC:2898]
E-value: 4.5e-72
Percent Identity: 38.0
Ensembl 97, assembly GRCh38.p12
dihydrolipoamide dehydrogenase [Source:HGNC Symbol;Acc:HGNC:2898]
E-value: 4.5e-72
Percent Identity: 38.0

References

No references are associated with this feature.