Burkholderia cenocepacia J2315, BCAS0593

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
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Gene Feature Overview

Strain Burkholderia cenocepacia J2315
GCF_000009485.1|latest
Locus Tag
BCAS0593
NCBI Locus TagQU43_RS71615
Name
Replicon chromosome 3
Genomic location 649453 - 650880 (+ strand)
CommentMember of rnd-1 operon encoding Resistance-Nodulation-Cell Division (RND) efflux pump RND-1

Cross-References

RefSeq WP_006489740.1
GI 197295434
Entrez 6804418
GI 197295434
INSDC CAR57525.1
NCBI Locus Tag QU43_RS71615
NCBI Old Locus Tag BCAS0593
RefSeq WP_006489740.1,GeneID
UniParc UPI00017BB05C
UniProtKB Acc B4ENY7
UniProtKB ID B4ENY7_BURCJ
UniRef100 UniRef100_B4ENY7
UniRef50 UniRef50_Q51487
UniRef90 UniRef90_A0A095FJT3

Product

Feature Type CDS
Coding Frame 1
Product Name
RND-1 efflux system outer membrane protein
Product Name Confidence: Class 1
Synonyms
Evidence for Translation
Charge (pH 7) -2.33
Kyte-Doolittle Hydrophobicity Value -0.210
Molecular Weight (kDa) 51307.0
Isoelectric Point (pI) 5.89

Subcellular localization

Individual Mappings
Localization Confidence PMID
Outer Membrane Class 3
Additional evidence for subcellular localization

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 311 genera

Orthologs/Comparative Genomics

Burkholderia Ortholog Group BG006899 (65 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: BCAS0593

References

Assessment of three Resistance-Nodulation-Cell Division drug efflux transporters of Burkholderia cenocepacia in intrinsic antibiotic resistance.
Buroni S, Pasca MR, Flannagan RS, Bazzini S, Milano A, Bertani I, Venturi V, Valvano MA, Riccardi G
BMC Microbiol 2009 Sep 17;9:200
PubMed ID: 19761586
Efflux pump-mediated drug resistance in Burkholderia.
Podnecky NL, Rhodes KA, Schweizer HP
Front Microbiol 2015;6:305
PubMed ID: 25926825