Burkholderia cenocepacia J2315, BCAM2748 (ecfK)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse

Gene Feature Overview

Strain Burkholderia cenocepacia J2315
GCF_000009485.1|latest
Locus Tag
BCAM2748
NCBI Locus TagQU43_RS68200
Name
ecfK
Replicon chromosome 2
Genomic location 3109088 - 3109981 (+ strand)

Cross-References

RefSeq YP_002235349.1
GI 206564586
Entrez 6930254
GI 206564586
INSDC CAR56612.1
NCBI Locus Tag QU43_RS68200
NCBI Old Locus Tag BCAM2748
RefSeq YP_002235349.1
UniParc UPI00017BA361
UniProtKB Acc B4ELE7
UniProtKB ID B4ELE7_BURCJ
UniRef100 UniRef100_A0A0D1DEN0
UniRef50 UniRef50_G7H8V7
UniRef90 UniRef90_G7H8V7

Product

Feature Type CDS
Coding Frame 1
Product Name
putative sigma factor
Product Name Confidence: Class 1
Synonyms sigma factor 70 EcfK
Evidence for Translation
Charge (pH 7) -3.92
Kyte-Doolittle Hydrophobicity Value -0.221
Molecular Weight (kDa) 33224.5
Isoelectric Point (pI) 6.25

Subcellular localization

Individual Mappings
Localization Confidence PMID
Cytoplasmic Class 3
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 189 genera

Orthologs/Comparative Genomics

Burkholderia Ortholog Group BG000010 (703 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: BCAM2748
Search term: ecfK

Human Homologs

References

Architecture of Burkholderia cepacia complex sigma70 gene family: evidence of alternative primary and clade-specific factors, and genomic instability.
Menard A, de Los Santos PE, Graindorge A, Cournoyer B
BMC Genomics 2007 Sep 4;8:308
PubMed ID: 17784948