Burkholderia cenocepacia J2315, BCAM2418

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
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Gene Feature Overview

Strain Burkholderia cenocepacia J2315
GCF_000009485.1|latest
Locus Tag
BCAM2418
Name
Replicon chromosome 2
Genomic location 2722300 - 2730627 (+ strand)
CommentComparative DNA sequence analysis of BCAM2418 genes (structural and promoter regions) of various B. cenocepacia isolates revealed that their lengths greatly vary according to the number of repetitive elements (PMID:32097539)

Cross-References

RefSeq YP_002235020.1
GI 206564257
Entrez 6929969
GI 206564257
INSDC CAR56282.1
RefSeq YP_002235020.1
UniParc UPI00017BA300
UniProtKB Acc B4EI37
UniProtKB ID B4EI37_BURCJ
UniRef100 UniRef100_B4EI37
UniRef50 UniRef50_Q3JLD6
UniRef90 UniRef90_B4EI37

Product

Feature Type CDS
Coding Frame 1
Product Name
trimeric autotransporter adhesin
Product Name Confidence: Class 1
Synonyms
Evidence for Translation
Charge (pH 7) -7.35
Kyte-Doolittle Hydrophobicity Value 0.069
Molecular Weight (kDa) 260114.0
Isoelectric Point (pI) 4.82

Subcellular localization

Individual Mappings
Localization Confidence PMID
Unknown (This protein may have multiple localization sites) Class 3
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 80 genera

Orthologs/Comparative Genomics

Burkholderia Ortholog Group BG002926 (1913 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: BCAM2418

Human Homologs

References

Trimeric autotransporter adhesins in members of the Burkholderia cepacia complex: a multifunctional family of proteins implicated in virulence.
Mil-Homens D, Fialho AM
Front Cell Infect Microbiol 2011;1:13
PubMed ID: 22919579
Burkholderia cenocepacia-host cell contact controls the transcription activity of the trimeric autotransporter adhesin BCAM2418 gene.
Pimenta AI, Mil-Homens D, Fialho AM
Microbiologyopen 2020 Apr;9(4):e998
PubMed ID: 32097539