Strain |
Burkholderia cenocepacia J2315
GCF_000009485.1|latest |
Locus Tag |
BCAM2307
|
NCBI Locus Tag | QU43_RS65910 |
Name |
zmpB
|
Replicon | chromosome 2 |
Genomic location | 2587413 - 2589125 (+ strand) |
RefSeq | WP_006483806.1 |
GI | 206564143 |
Entrez | 6929882 |
GI | 206564143 |
INSDC | CAR56166.1 |
NCBI Locus Tag | QU43_RS65910 |
NCBI Old Locus Tag | BCAM2307 |
RefSeq | WP_006483806.1,GeneID |
UniParc | UPI00017BA06B |
UniProtKB Acc | B4EHF6 |
UniProtKB ID | B4EHF6_BURCJ |
UniRef100 | UniRef100_B4EHF6 |
UniRef50 | UniRef50_B4EHF6 |
UniRef90 | UniRef90_B4EHF6 |
Feature Type | CDS |
Coding Frame | 1 |
Product Name |
zinc metalloprotease ZmpB
|
Synonyms | |
Evidence for Translation | |
Charge (pH 7) | -4.72 |
Kyte-Doolittle Hydrophobicity Value | -0.276 |
Molecular Weight (kDa) | 60547.5 |
Isoelectric Point (pI) | 6.19 |
Individual Mappings | |
Additional evidence for subcellular localization |
Source 1 | |
Database | BGD |
Category | ZmpB protease |
Evidence |
ECO:0000250
sequence similarity evidence used in manual assertion
|
Host Organism | Rattus norvegicus |
Notes | zmpB mutant in K56-2 is attenuated for virulence in agar bead model of chronic lung infection |
Reference | 16790782 |
Results |
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 20 genera
|
Burkholderia Ortholog Group |
BG004001 (573 members) |
Putative Inparalogs | None Found |
STRING database | Search for predicted protein-protein interactions using:
Search term: BCAM2307
Search term: zmpB
Search term: zinc metalloprotease ZmpB
|
Burkholderia cenocepacia type VI secretion system mediates escape of type II secreted proteins into the cytoplasm of infected macrophages.
Rosales-Reyes R, Aubert DF, Tolman JS, Amer AO, Valvano MA
PLoS One 2012;7(7):e41726
PubMed ID: 22848580
|
Burkholderia cenocepacia ZmpB is a broad-specificity zinc metalloprotease involved in virulence.
Kooi C, Subsin B, Chen R, Pohorelic B, Sokol PA
Infect Immun 2006 Jul;74(7):4083-93
PubMed ID: 16790782
|