Burkholderia cenocepacia J2315, BCAM2227 (pchG)

Gene Feature Overview

Strain	Burkholderia cenocepacia J2315 GCF_000009485.1|latest
Locus Tag	BCAM2227
NCBI Locus Tag	QU43_RS65505
Name	pchG
Replicon	chromosome 2
Genomic location	2490165 - 2491217 (- strand)

Cross-References

RefSeq	WP_006493253.1
GI	206564064
Entrez	6929813
GI	206564064
INSDC	CAR56085.1
NCBI Locus Tag	QU43_RS65505
NCBI Old Locus Tag	BCAM2227
RefSeq	WP_006493253.1,GeneID
UniParc	UPI00017BA01D
UniProtKB Acc	B4EGF9
UniProtKB ID	B4EGF9_BURCJ
UniRef100	UniRef100_A0A095F9J3
UniRef50	UniRef50_Q9HWG5
UniRef90	UniRef90_B1K7P8

Product

Feature Type	CDS
Coding Frame	1
Product Name	putative pyochelin biosynthetic protein PchG
Synonyms
Evidence for Translation
Charge (pH 7)	-6.28
Kyte-Doolittle Hydrophobicity Value	0.167
Molecular Weight (kDa)	36893.7
Isoelectric Point (pI)	5.59

Subcellular localization

Individual Mappings	Localization Confidence PMID Cytoplasmic Class 3 20472543
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

Pathogen Association Analysis

Results

Common Found in both pathogen and nonpathogenic strains Hits to this gene were found in 38 genera

Orthologs/Comparative Genomics

Burkholderia Ortholog Group	BG006693 (375 members)
Putative Inparalogs	None Found

Interactions

STRING database

Search for predicted protein-protein interactions using: Search term: BCAM2227 Search term: pchG Search term: putative pyochelin biosynthetic protein PchG

Human Homologs

References

Dihydroaeruginoic acid synthetase and pyochelin synthetase, products of the pchEF genes, are induced by extracellular pyochelin in Pseudomonas aeruginosa. Reimmann C, Serino L, Beyeler M, Haas D Microbiology 1998 Nov;144 ( Pt 11):3135-48 PubMed ID: 9846750

Erratum in: J Bacteriol. 2009 Apr;191(8):2907. The genome of Burkholderia cenocepacia J2315, an epidemic pathogen of cystic fibrosis patients. J Bacteriol. 2009 Jan;191(1):261-77. PubMed ID: 18931103