Burkholderia cenocepacia J2315, BCAM1870 (cepI)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
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Gene Feature Overview

Strain Burkholderia cenocepacia J2315
GCF_000009485.1|latest
Locus Tag
BCAM1870
NCBI Locus TagQU43_RS63750
Name
cepI
Replicon chromosome 2
Genomic location 2088184 - 2088792 (+ strand)

Cross-References

RefSeq WP_006483943.1
GI 206563718
Entrez 6929503
GI 206563718
INSDC CAR55728.1
NCBI Locus Tag QU43_RS63750
NCBI Old Locus Tag BCAM1870
RefSeq WP_006483943.1,GeneID
UniParc UPI00000B9C1D
UniProtKB Acc B4EMD2
UniProtKB ID B4EMD2_BURCJ
UniRef100 UniRef100_B4EMD2
UniRef50 UniRef50_O30920
UniRef90 UniRef90_B4EMD2

Product

Feature Type CDS
Coding Frame 1
Product Name
N-acylhomoserine lactone synthase CepI
Product Name Confidence: Class 1
Synonyms acyl-homoserine lactone synthase CepI
Evidence for Translation
Charge (pH 7) -5.16
Kyte-Doolittle Hydrophobicity Value -0.112
Molecular Weight (kDa) 22263.1
Isoelectric Point (pI) 5.08

Subcellular localization

Individual Mappings
Localization Confidence PMID
Cytoplasmic Class 3
Additional evidence for subcellular localization

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 63 genera

Orthologs/Comparative Genomics

Burkholderia Ortholog Group BG003720 (981 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: BCAM1870
Search term: cepI

References

Distribution of quorum-sensing genes in the Burkholderia cepacia complex.
Lutter E, Lewenza S, Dennis JJ, Visser MB, Sokol PA
Infect Immun 2001 Jul;69(7):4661-6
PubMed ID: 11402012
The cep quorum-sensing system of Burkholderia cepacia H111 controls biofilm formation and swarming motility.
Huber B, Riedel K, Hentzer M, Heydorn A, Gotschlich A, Givskov M, Molin S, Eberl L
Microbiology 2001 Sep;147(Pt 9):2517-2528
PubMed ID: 11535791
Characterization of the cciIR quorum-sensing system in Burkholderia cenocepacia.
Malott RJ, Baldwin A, Mahenthiralingam E, Sokol PA
Infect Immun 2005 Aug;73(8):4982-92
PubMed ID: 16041013