Burkholderia cenocepacia J2315, BCAM1259 (sigJ)

Gene Feature Overview

Strain	Burkholderia cenocepacia J2315 GCF_000009485.1|latest
Locus Tag	BCAM1259
NCBI Locus Tag	QU43_RS60645
Name	sigJ
Replicon	chromosome 2
Genomic location	1382085 - 1383611 (- strand)

Cross-References

RefSeq	WP_006484701.1
GI	206563110
Entrez	6928938
GI	206563110
INSDC	CAR55114.1
NCBI Locus Tag	QU43_RS60645
NCBI Old Locus Tag	BCAM1259
RefSeq	WP_006484701.1,GeneID
UniParc	UPI00017B9FA9
UniProtKB Acc	B4EHD8
UniProtKB ID	B4EHD8_BURCJ
UniRef100	UniRef100_B4EHD8
UniRef50	UniRef50_A9ALE2
UniRef90	UniRef90_A0AZP2

Product

Feature Type	CDS
Coding Frame	1
Product Name	RNA polymerase sigma factor Product Name Confidence: Class 1
Synonyms	sigma factor 70 SigJ
Evidence for Translation
Charge (pH 7)	-10.41
Kyte-Doolittle Hydrophobicity Value	-0.216
Molecular Weight (kDa)	54772.0
Isoelectric Point (pI)	5.39

Subcellular localization

Individual Mappings	Localization Confidence PMID Cytoplasmic Class 3 20472543
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

Pathogen Association Analysis

Results

Common Found in both pathogen and nonpathogenic strains Hits to this gene were found in 591 genera

Orthologs/Comparative Genomics

Burkholderia Ortholog Group	BG003244 (490 members)
Putative Inparalogs	None Found

Interactions

STRING database

Search for predicted protein-protein interactions using: Search term: BCAM1259 Search term: sigJ Search term: RNA polymerase sigma factor

Human Homologs

References

Architecture of Burkholderia cepacia complex sigma70 gene family: evidence of alternative primary and clade-specific factors, and genomic instability. Menard A, de Los Santos PE, Graindorge A, Cournoyer B BMC Genomics 2007 Sep 4;8:308 PubMed ID: 17784948