Burkholderia cenocepacia J2315, BCAM0849 (ecfL)

Gene Feature Overview

Strain	Burkholderia cenocepacia J2315 GCF_000009485.1|latest
Locus Tag	BCAM0849
NCBI Locus Tag	QU43_RS58625
Name	ecfL
Replicon	chromosome 2
Genomic location	934738 - 936006 (+ strand)

Cross-References

RefSeq	WP_006482940.1
GI	206562706
Entrez	6928604
GI	206562706
INSDC	CAR54707.1
NCBI Locus Tag	QU43_RS58625
NCBI Old Locus Tag	BCAM0849
RefSeq	WP_006482940.1,GeneID
UniParc	UPI00017B99E9
UniProtKB Acc	B4EMQ1
UniProtKB ID	B4EMQ1_BURCJ
UniRef100	UniRef100_A0A095ECA5
UniRef50	UniRef50_C5CSL3
UniRef90	UniRef90_A4JLM3

Product

Feature Type	CDS
Coding Frame	1
Product Name	putative RNA polymerase sigma factor Product Name Confidence: Class 1
Synonyms	sigma factor 70 EcfL
Evidence for Translation
Charge (pH 7)	-7.18
Kyte-Doolittle Hydrophobicity Value	0.007
Molecular Weight (kDa)	45927.1
Isoelectric Point (pI)	5.96

Subcellular localization

Individual Mappings	Localization Confidence PMID Cytoplasmic Class 3 20472543
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

Pathogen Association Analysis

Results

Common Found in both pathogen and nonpathogenic strains Hits to this gene were found in 152 genera

Orthologs/Comparative Genomics

Burkholderia Ortholog Group	BG004844 (654 members)
Putative Inparalogs	None Found

Interactions

STRING database

Search for predicted protein-protein interactions using: Search term: BCAM0849 Search term: ecfL Search term: putative RNA polymerase sigma factor

Human Homologs

References

Architecture of Burkholderia cepacia complex sigma70 gene family: evidence of alternative primary and clade-specific factors, and genomic instability. Menard A, de Los Santos PE, Graindorge A, Cournoyer B BMC Genomics 2007 Sep 4;8:308 PubMed ID: 17784948