Burkholderia cenocepacia J2315, BCAM0449 (copC)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
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Gene Feature Overview

Strain Burkholderia cenocepacia J2315
GCF_000009485.1|latest
Locus Tag
BCAM0449
NCBI Locus TagQU43_RS56640
Name
copC
Replicon chromosome 2
Genomic location 503462 - 503842 (+ strand)

Cross-References

RefSeq WP_006484606.1
GI 206562312
Entrez 6928226
GI 206562312
INSDC CAR54307.1
NCBI Locus Tag QU43_RS56640
NCBI Old Locus Tag BCAM0449
RefSeq WP_006484606.1,GeneID
UniParc UPI00017B9CB9
UniProtKB Acc B4EJH2
UniProtKB ID B4EJH2_BURCJ
UniRef100 UniRef100_G7HEY8
UniRef50 UniRef50_A9AU76
UniRef90 UniRef90_A0A095E8S4

Product

Feature Type CDS
Coding Frame 1
Product Name
CopC
Product Name Confidence: Class 2
Synonyms
Evidence for Translation
Charge (pH 7) 4.46
Kyte-Doolittle Hydrophobicity Value 0.153
Molecular Weight (kDa) 12967.7
Isoelectric Point (pI) 10.32

Subcellular localization

Individual Mappings
Localization Confidence PMID
Periplasmic Class 3
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 142 genera

Orthologs/Comparative Genomics

Burkholderia Ortholog Group BG004580 (578 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: BCAM0449
Search term: copC
Search term: CopC

Human Homologs

References

Copper resistance genes of Burkholderia cenocepacia H111 identified by transposon sequencing.
Higgins S, Gualdi S, Pinto-Carbó M, Eberl L
Environ Microbiol Rep 2020 Apr;12(2):241-249
PubMed ID: 32090500