Burkholderia cenocepacia J2315, BCAM0442 (copS)

Gene Feature Overview

Strain	Burkholderia cenocepacia J2315 GCF_000009485.1|latest
Locus Tag	BCAM0442
NCBI Locus Tag	QU43_RS56605
Name	copS
Replicon	chromosome 2
Genomic location	497179 - 498588 (- strand)

Cross-References

RefSeq	WP_006484515.1
GI	206562305
Entrez	6928220
GI	206562305
INSDC	CAR54300.1
NCBI Locus Tag	QU43_RS56605
NCBI Old Locus Tag	BCAM0442
RefSeq	WP_006484515.1,GeneID
UniParc	UPI00017B9CB2
UniProtKB Acc	B4EJG5
UniProtKB ID	B4EJG5_BURCJ
UniRef100	UniRef100_B4EJG5
UniRef50	UniRef50_A9AU83
UniRef90	UniRef90_G7HEZ6

Product

Feature Type	CDS
Coding Frame	1
Product Name	CopS Product Name Confidence: Class 2
Synonyms
Evidence for Translation
Charge (pH 7)	0.81
Kyte-Doolittle Hydrophobicity Value	-0.066
Molecular Weight (kDa)	50957.0
Isoelectric Point (pI)	7.16

Subcellular localization

Individual Mappings	Localization Confidence PMID Cytoplasmic Membrane Class 3 20472543
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

Pathogen Association Analysis

Results

Common Found in both pathogen and nonpathogenic strains Hits to this gene were found in 620 genera

Orthologs/Comparative Genomics

Burkholderia Ortholog Group	BG004575 (943 members)
Putative Inparalogs	None Found

Interactions

STRING database

Search for predicted protein-protein interactions using: Search term: BCAM0442 Search term: copS Search term: CopS

Human Homologs

References

Identification of a copper-responsive two-component system on the chromosome of Escherichia coli K-12. Munson GP, Lam DL, Outten FW, O'Halloran TV J Bacteriol 2000 Oct;182(20):5864-71 PubMed ID: 11004187