Burkholderia cenocepacia J2315, BCAM0239a (cciI)

Gene Feature Overview

Strain	Burkholderia cenocepacia J2315 GCF_000009485.1|latest
Locus Tag	BCAM0239a
NCBI Locus Tag	QU43_RS55620
Name	cciI
Replicon	chromosome 2
Genomic location	296654 - 297277 (- strand)

Cross-References

RefSeq	YP_002232872.1
GI	206562109
Entrez	6928036
GI	206562109
INSDC	CAR54099.1
NCBI Locus Tag	QU43_RS55620
NCBI Old Locus Tag	BCAM0239a
RefSeq	WP_012493039.1,GeneID
UniParc	UPI00017B9A0B
UniProtKB Acc	B4EI52
UniProtKB ID	B4EI52_BURCJ
UniRef100	UniRef100_B4EI52
UniRef50	UniRef50_B4EI52
UniRef90	UniRef90_B4EI52

Product

Feature Type	CDS
Coding Frame	1
Product Name	N-acylhomoserine lactone synthase Product Name Confidence: Class 1
Synonyms
Evidence for Translation
Charge (pH 7)	2.21
Kyte-Doolittle Hydrophobicity Value	0.239
Molecular Weight (kDa)	22373.6
Isoelectric Point (pI)	7.79

Subcellular localization

Individual Mappings	Localization Confidence PMID Unknown Class 3 20472543
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

Pathogen Association Analysis

Results

Common Found in both pathogen and nonpathogenic strains Hits to this gene were found in 45 genera

Orthologs/Comparative Genomics

Burkholderia Ortholog Group	BG003720 (981 members)
Putative Inparalogs	None Found

Interactions

STRING database

Search for predicted protein-protein interactions using: Search term: BCAM0239a Search term: cciI Search term: N-acylhomoserine lactone synthase

Human Homologs

References

The Burkholderia cepacia epidemic strain marker is part of a novel genomic island encoding both virulence and metabolism-associated genes in Burkholderia cenocepacia. Baldwin A, Sokol PA, Parkhill J, Mahenthiralingam E Infect Immun 2004 Mar;72(3):1537-47 PubMed ID: 14977960

Characterization of the cciIR quorum-sensing system in Burkholderia cenocepacia. Malott RJ, Baldwin A, Mahenthiralingam E, Sokol PA Infect Immun 2005 Aug;73(8):4982-92 PubMed ID: 16041013