Burkholderia cenocepacia J2315, BCAL2360 (ecfD)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
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Gene Feature Overview

Strain Burkholderia cenocepacia J2315
GCF_000009485.1|latest
Locus Tag
BCAL2360
NCBI Locus TagQU43_RS48455
Name
ecfD
Replicon chromosome 1
Genomic location 2615164 - 2615727 (+ strand)

Cross-References

RefSeq WP_006491033.1
GI 206560719
Entrez 6933756
GI 206560719
INSDC CAR52661.1
NCBI Locus Tag QU43_RS48455
NCBI Old Locus Tag BCAL2360
RefSeq WP_006491033.1,GeneID
UniParc UPI00017B97D9
UniProtKB Acc B4E5N8
UniProtKB ID B4E5N8_BURCJ
UniRef100 UniRef100_A0A095DSA3
UniRef50 UniRef50_Q0KCU5
UniRef90 UniRef90_A0A071M5F0

Product

Feature Type CDS
Coding Frame 1
Product Name
RNA polymerase factor sigma-70
Product Name Confidence: Class 1
Synonyms sigma factor 70 EcfD
Evidence for Translation
Charge (pH 7) -11.09
Kyte-Doolittle Hydrophobicity Value -0.487
Molecular Weight (kDa) 21176.5
Isoelectric Point (pI) 4.53

Subcellular localization

Individual Mappings
Localization Confidence PMID
Cytoplasmic Class 3
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 179 genera

Orthologs/Comparative Genomics

Burkholderia Ortholog Group BG002152 (654 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: BCAL2360
Search term: ecfD

Human Homologs

References

Architecture of Burkholderia cepacia complex sigma70 gene family: evidence of alternative primary and clade-specific factors, and genomic instability.
Menard A, de Los Santos PE, Graindorge A, Cournoyer B
BMC Genomics 2007 Sep 4;8:308
PubMed ID: 17784948