Burkholderia pseudomallei 668, BURPS668_0018 (gspM)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown

Gene Feature Overview

Strain Burkholderia pseudomallei 668
GCF_000015905.1|latest
Locus Tag
BURPS668_0018
NCBI Locus TagBURPS668_RS00085
Name
gspM
Replicon chromosome I
Genomic location 18904 - 19410 (+ strand)

Cross-References

RefSeq WP_004524542.1
GI 126441244
Entrez 4881933
GI 126441244
INSDC ABN84243.1
NCBI Locus Tag BURPS668_RS00085
NCBI Old Locus Tag BURPS668_0018
RefSeq WP_004524542.1
UniParc UPI00000B81F5
UniProtKB Acc A3N402
UniProtKB ID A3N402_BURP6
UniRef100 UniRef100_A3NPN2
UniRef50 UniRef50_B4E6P7
UniRef90 UniRef90_A3NPN2

Product

Feature Type CDS
Coding Frame 1
Product Name
general secretory pathway protein M
Product Name Confidence: Class 1
Synonyms
Evidence for Translation
Charge (pH 7) -0.29
Kyte-Doolittle Hydrophobicity Value -0.041
Molecular Weight (kDa) 17939.3
Isoelectric Point (pI) 6.81

Subcellular localization

Individual Mappings
Localization Confidence PMID
Unknown Class 3
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 10 genera

Orthologs/Comparative Genomics

Burkholderia Ortholog Group BG000039 (654 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: BURPS668_0018
Search term: gspM

Human Homologs

References

Molecular characterization of genetic loci required for secretion of exoproducts in Burkholderia pseudomallei.
DeShazer D, Brett PJ, Burtnick MN, Woods DE
J Bacteriol 1999 Aug;181(15):4661-4
PubMed ID: 10419967
Proteomic analysis of the Burkholderia pseudomallei type II secretome reveals hydrolytic enzymes, novel proteins, and the deubiquitinase TssM.
Burtnick MN, Brett PJ, DeShazer D
Infect Immun 2014 Aug;82(8):3214-26
PubMed ID: 24866793