Burkholderia pseudomallei 668, BURPS668_0004 (hupA)

Gene Feature Overview

Strain	Burkholderia pseudomallei 668 GCF_000015905.1|latest
Locus Tag	BURPS668_0004
NCBI Locus Tag	BURPS668_RS00020
Name	hupA
Replicon	chromosome I
Genomic location	5479 - 5757 (+ strand)

Cross-References

RefSeq	WP_004195781.1
GI	126442121
Entrez	4883257
GI	126442121
INSDC	ABN85120.1
NCBI Locus Tag	BURPS668_RS00020
NCBI Old Locus Tag	BURPS668_0004
RefSeq	WP_004195781.1
UniParc	UPI0000128EF2
UniProtKB Acc	A3N3Y8
UniProtKB ID	A3N3Y8_BURP6
UniRef100	UniRef100_I1WEI8
UniRef50	UniRef50_I1WEI8
UniRef90	UniRef90_I1WEI8

Product

Feature Type	CDS
Coding Frame	1
Product Name	DNA-binding protein HU-alpha
Synonyms
Evidence for Translation
Charge (pH 7)	8.98
Kyte-Doolittle Hydrophobicity Value	-0.386
Molecular Weight (kDa)	9621.0
Isoelectric Point (pI)	10.99

Subcellular localization

Individual Mappings	Localization Confidence PMID Cytoplasmic Class 3 20472543
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

PDB 3D Structures

Accession	Header	Accession Date	Compound	Source	Resolution	Method	Percent Identity
6N2L	DNA BINDING PROTEIN	11/13/18	Crystal structure of a histone family protein DNA-binding protein from Burkholderia ambifaria	BURKHOLDERIA AMBIFARIA (STRAIN MC40-6)	1.85	X-RAY DIFFRACTION	98.9

Pathogen Association Analysis

Results

Common Found in both pathogen and nonpathogenic strains Hits to this gene were found in 569 genera

Orthologs/Comparative Genomics

Burkholderia Ortholog Group	BG000052 (653 members)
Putative Inparalogs	None Found

Interactions

STRING database

Search for predicted protein-protein interactions using: Search term: BURPS668_0004 Search term: hupA Search term: DNA-binding protein HU-alpha

Human Homologs

References