Burkholderia mallei ATCC 23344, BMAA1541 (bsaR)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
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Gene Feature Overview

Strain Burkholderia mallei ATCC 23344
GCF_000011705.1|latest
Locus Tag
BMAA1541
Name
bsaR
Replicon chromosome 2
Genomic location 1669432 - 1669839 (- strand)
CommentThis gene is part of the Burkholderia mallei type III secretion system T3SS-3 gene locus.

Cross-References

RefSeq YP_106130.1
GI 53716342
NCBI Locus Tag BMAA1541
RefSeq YP_106130.1,GeneID

Product

Feature Type CDS
Coding Frame 1
Product Name
chaperone protein BsaR (T3SS-3)
Product Name Confidence: Class 2
Synonyms type III secretion system protein BsaR
Evidence for Translation
Charge (pH 7) -10.23
Kyte-Doolittle Hydrophobicity Value 0.182
Molecular Weight (kDa) 14837.8
Isoelectric Point (pI) 4.36

Subcellular localization

Individual Mappings
Localization Confidence PMID
Cytoplasmic Class 3
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Virulence Evidence

Source 1
Database VFDB : VF0428
Category T3SS-3
Evidence ECO:0000250
sequence similarity evidence used in manual assertion
Host Organism
Notes
Annotation transferred from Burkholderia pseudomallei K96243
Reference 17984080

Pathogen Association Analysis

Results Analysis not done

Orthologs/Comparative Genomics

Burkholderia Ortholog Group BG019846 (320 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: BMAA1541
Search term: bsaR

Human Homologs

References

Type III Secretion in the Melioidosis Pathogen <i>Burkholderia pseudomallei</i>.
Vander Broek CW, Stevens JM
Front Cell Infect Microbiol 2017;7:255
PubMed ID: 28664152
A genome-wide screen identifies a Bordetella type III secretion effector and candidate effectors in other species.
Panina EM, Mattoo S, Griffith N, Kozak NA, Yuk MH, Miller JF
Mol Microbiol 2005 Oct;58(1):267-79
PubMed ID: 16164564
InvB is a type III secretion-associated chaperone for the Salmonella enterica effector protein SopE.
Lee SH, Galán JE
J Bacteriol 2003 Dec;185(24):7279-84
PubMed ID: 14645290