Burkholderia cenocepacia MC0-3, Bcenmc03_6383 (aidA)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown

Gene Feature Overview

Strain Burkholderia cenocepacia MC0-3
GCF_000019505.1|latest
Locus Tag
Bcenmc03_6383
NCBI Locus TagBCENMC03_RS31915
Name
aidA
Replicon chromosome 3
Genomic location 418147 - 418650 (+ strand)

Cross-References

RefSeq WP_006483191.1
GI 170734879
Entrez 6125306
GI 170734879
INSDC ACA95498.1
NCBI Locus Tag BCENMC03_RS31915
NCBI Old Locus Tag Bcenmc03_6383
RefSeq WP_006483191.1
UniParc UPI000052DF38
UniProtKB Acc B1KBA1
UniProtKB ID B1KBA1_BURCC
UniRef100 UniRef100_A0A071M2V9
UniRef50 UniRef50_Q39MR0
UniRef90 UniRef90_Q39MR0

Product

Feature Type CDS
Coding Frame 1
Product Name
hypothetical protein
Product Name Confidence: Class 2
Synonyms nematocidal protein AidA
Evidence for Translation
Charge (pH 7) -0.66
Kyte-Doolittle Hydrophobicity Value -0.266
Molecular Weight (kDa) 18871.3
Isoelectric Point (pI) 6.50

Subcellular localization

Individual Mappings
Localization Confidence PMID
Unknown Class 3
Cytoplasmic Class 3
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 13 genera

Orthologs/Comparative Genomics

Burkholderia Ortholog Group BG004444 (417 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: Bcenmc03_6383
Search term: aidA

Human Homologs

References

Identification of a novel virulence factor in Burkholderia cenocepacia H111 required for efficient slow killing of Caenorhabditis elegans.
Huber B, Feldmann F, Köthe M, Vandamme P, Wopperer J, Riedel K, Eberl L
Infect Immun 2004 Dec;72(12):7220-30
PubMed ID: 15557647