Burkholderia cenocepacia MC0-3, Bcenmc03_0032 (ecfB)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown

Gene Feature Overview

Strain Burkholderia cenocepacia MC0-3
GCF_000019505.1|latest
Locus Tag
Bcenmc03_0032
NCBI Locus TagBCENMC03_RS00185
Name
ecfB
Replicon chromosome 1
Genomic location 47442 - 47963 (+ strand)

Cross-References

RefSeq WP_006477208.1
GI 170731387
Entrez 6121715
GI 170731387
INSDC ACA89212.1
NCBI Locus Tag BCENMC03_RS00185
NCBI Old Locus Tag Bcenmc03_0032
RefSeq WP_006477208.1
UniParc UPI00006D9CBE
UniProtKB Acc B1K1C4
UniProtKB ID B1K1C4_BURCC
UniRef100 UniRef100_B1K1C4
UniRef50 UniRef50_A0A0A3ZSI7
UniRef90 UniRef90_G7HDC5

Product

Feature Type CDS
Coding Frame 1
Product Name
ECF subfamily RNA polymerase sigma-24 factor
Product Name Confidence: Class 1
Synonyms sigma factor 70 EcfB
Evidence for Translation
Charge (pH 7) 2.48
Kyte-Doolittle Hydrophobicity Value -0.350
Molecular Weight (kDa) 19952.5
Isoelectric Point (pI) 9.65

Subcellular localization

Individual Mappings
Localization Confidence PMID
Cytoplasmic Membrane Class 3
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 445 genera

Orthologs/Comparative Genomics

Burkholderia Ortholog Group BG000007 (617 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: Bcenmc03_0032
Search term: ecfB

Human Homologs

References

Architecture of Burkholderia cepacia complex sigma70 gene family: evidence of alternative primary and clade-specific factors, and genomic instability.
Menard A, de Los Santos PE, Graindorge A, Cournoyer B
BMC Genomics 2007 Sep 4;8:308
PubMed ID: 17784948