Burkholderia cenocepacia MC0-3, Bcenmc03_1599

Gene Feature Overview

Strain	Burkholderia cenocepacia MC0-3 GCF_000019505.1|latest
Locus Tag	Bcenmc03_1599
NCBI Locus Tag	BCENMC03_RS08115
Name
Replicon	chromosome 1
Genomic location	1766424 - 1769564 (+ strand)

Cross-References

RefSeq	WP_012328444.1
GI	170732947
Entrez	6123275
GI	170732947
NCBI Locus Tag	BCENMC03_RS08115
NCBI Old Locus Tag	Bcenmc03_1599
RefSeq	WP_012328444.1
UniProtKB Acc	B1K118
UniProtKB ID	B1K118_BURCC

Product

Feature Type	CDS
Coding Frame	1
Product Name	multidrug efflux protein
Synonyms
Evidence for Translation
Charge (pH 7)	8.17
Kyte-Doolittle Hydrophobicity Value	0.341
Molecular Weight (kDa)	111646.5
Isoelectric Point (pI)	9.26

Subcellular localization

Individual Mappings	Localization Confidence PMID Cytoplasmic Membrane Class 3 20472543
Additional evidence for subcellular localization

AMR gene predictions from CARD database

Identified using the Resistance Gene Identifier (RGI)

Model Name	Definition	Accession	Model Type (?)	SNP	Cutoff	Bit Score	Percent Identity	CARD Version
amrB	amrB is the membrane fusion protein of the AmrAB-OprM multidrug efflux complex.	ARO:3002983	protein homolog model		Strict	0.0	86.5	1.2.1

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

Pathogen Association Analysis

Results

Common Found in both pathogen and nonpathogenic strains Hits to this gene were found in 486 genera

Orthologs/Comparative Genomics

Burkholderia Ortholog Group	BG001444 (2569 members)
Putative Inparalogs	None Found

Interactions

STRING database

Search for predicted protein-protein interactions using: Search term: Bcenmc03_1599 Search term: multidrug efflux protein

Human Homologs

References