Burkholderia cenocepacia MC0-3, Bcenmc03_0253 (fliA)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown

Gene Feature Overview

Strain Burkholderia cenocepacia MC0-3
GCF_000019505.1|latest
Locus Tag
Bcenmc03_0253
NCBI Locus TagBCENMC03_RS01290
Name
fliA
Replicon chromosome 1
Genomic location 281706 - 282437 (+ strand)

Cross-References

RefSeq WP_011546702.1
GI 170731608
Entrez 6121936
GI 170731608
INSDC ACA89433.1
NCBI Locus Tag BCENMC03_RS01290
NCBI Old Locus Tag Bcenmc03_0253
RefSeq WP_011546702.1
UniParc UPI000052DCAE
UniProtKB Acc B1JTJ3
UniProtKB ID B1JTJ3_BURCC
UniRef100 UniRef100_B1JTJ3
UniRef50 UniRef50_B1JTJ3
UniRef90 UniRef90_B1JTJ3

Product

Feature Type CDS
Coding Frame 1
Product Name
flagellar biosynthesis sigma factor
Synonyms
Evidence for Translation
Charge (pH 7) -11.10
Kyte-Doolittle Hydrophobicity Value -0.472
Molecular Weight (kDa) 27731.0
Isoelectric Point (pI) 4.86

Subcellular localization

Individual Mappings
Localization Confidence PMID
Cytoplasmic Class 3
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

Virulence Evidence

Source 1
Database VFDB : VF0430
Category Flagella
Evidence ECO:0000250
sequence similarity evidence used in manual assertion
Host Organism
Notes
Annotation transferred from Burkholderia pseudomallei K96243
Reference 17984080

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 585 genera

Orthologs/Comparative Genomics

Burkholderia Ortholog Group BG000177 (655 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: Bcenmc03_0253
Search term: fliA

Human Homologs

References

Architecture of Burkholderia cepacia complex sigma70 gene family: evidence of alternative primary and clade-specific factors, and genomic instability.
Menard A, de Los Santos PE, Graindorge A, Cournoyer B
BMC Genomics 2007 Sep 4;8:308
PubMed ID: 17784948