Burkholderia vietnamiensis G4, Bcep1808_4471 (bceM)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
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Gene Feature Overview

Strain Burkholderia vietnamiensis G4
GCF_000016205.1|latest
Locus Tag
Bcep1808_4471
NCBI Locus TagBCEP1808_RS22340
Name
bceM
Synonym: `
Replicon chromosome 2
Genomic location 1310148 - 1311116 (- strand)

Cross-References

RefSeq WP_011881770.1
GI 134293165
Entrez 4950689
GI 134293165
NCBI Locus Tag BCEP1808_RS22340
NCBI Old Locus Tag Bcep1808_4471
RefSeq WP_011881770.1
UniProtKB Acc A4JMD3
UniProtKB ID A4JMD3_BURVG

Product

Feature Type CDS
Coding Frame 1
Product Name
BceM
Product Name Confidence: Class 2
Synonyms NAD-dependent epimerase/dehydratase
Evidence for Translation
Charge (pH 7) 3.14
Kyte-Doolittle Hydrophobicity Value -0.059
Molecular Weight (kDa) 34690.0
Isoelectric Point (pI) 8.60

Subcellular localization

Individual Mappings
Localization Confidence PMID
Cytoplasmic Class 3
Unknown Class 3
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

PDB 3D Structures

Accession Header Accession Date Compound Source Resolution Method Percent Identity
4LW8 ISOMERASE 07/26/13 Crystal structure of a putative epimerase from Burkholderia cenocepacia J2315 BURKHOLDERIA CENOCEPACIA 2.1 X-RAY DIFFRACTION 92.7

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 635 genera

Orthologs/Comparative Genomics

Burkholderia Ortholog Group BG000738 (646 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: Bcep1808_4471
Search term: bceM
Search term: BceM

Human Homologs

References

Distribution of cepacian biosynthesis genes among environmental and clinical Burkholderia strains and role of cepacian exopolysaccharide in resistance to stress conditions.
Ferreira AS, Leitão JH, Silva IN, Pinheiro PF, Sousa SA, Ramos CG, Moreira LM
Appl Environ Microbiol 2010 Jan;76(2):441-50
PubMed ID: 19948863