Burkholderia vietnamiensis G4, Bcep1808_4205 (bceF)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
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Gene Feature Overview

Strain Burkholderia vietnamiensis G4
GCF_000016205.1|latest
Locus Tag
Bcep1808_4205
NCBI Locus TagBCEP1808_RS21030
Name
bceF
Replicon chromosome 2
Genomic location 1013024 - 1015249 (+ strand)

Cross-References

RefSeq WP_011881537.1
GI 134292914
Entrez 4950422
GI 134292914
INSDC ABO57185.1
NCBI Locus Tag BCEP1808_RS21030
NCBI Old Locus Tag Bcep1808_4205
RefSeq WP_011881537.1
UniParc UPI00003A5283
UniProtKB Acc A4JLN2
UniProtKB ID A4JLN2_BURVG
UniRef100 UniRef100_A4JLN2
UniRef50 UniRef50_A9ANS7
UniRef90 UniRef90_A9ANS7

Product

Feature Type CDS
Coding Frame 1
Product Name
BceF
Product Name Confidence: Class 2
Product Name Confidence: Class 1
Synonyms lipopolysaccharide biosynthesis protein
tyrosine autokinase BceF
Evidence for Translation
Charge (pH 7) -0.83
Kyte-Doolittle Hydrophobicity Value -0.047
Molecular Weight (kDa) 79975.1
Isoelectric Point (pI) 6.82

Subcellular localization

Individual Mappings
Localization Confidence PMID
Cytoplasmic Membrane Class 3
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 468 genera

Orthologs/Comparative Genomics

Burkholderia Ortholog Group BG004851 (638 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: Bcep1808_4205
Search term: bceF
Search term: BceF

Human Homologs

References

Functional analysis of Burkholderia cepacia genes bceD and bceF, encoding a phosphotyrosine phosphatase and a tyrosine autokinase, respectively: role in exopolysaccharide biosynthesis and biofilm formation.
Ferreira AS, Leitão JH, Sousa SA, Cosme AM, Sá-Correia I, Moreira LM
Appl Environ Microbiol 2007 Jan;73(2):524-34
PubMed ID: 17114319
Distribution of cepacian biosynthesis genes among environmental and clinical Burkholderia strains and role of cepacian exopolysaccharide in resistance to stress conditions.
Ferreira AS, Leitão JH, Silva IN, Pinheiro PF, Sousa SA, Ramos CG, Moreira LM
Appl Environ Microbiol 2010 Jan;76(2):441-50
PubMed ID: 19948863