Burkholderia vietnamiensis G4, Bcep1808_4203 (bceD)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
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Gene Feature Overview

Strain Burkholderia vietnamiensis G4
GCF_000016205.1|latest
Locus Tag
Bcep1808_4203
NCBI Locus TagBCEP1808_RS21020
Name
bceD
Replicon chromosome 2
Genomic location 1011358 - 1011801 (+ strand)

Cross-References

RefSeq WP_011881535.1
GI 134292912
Entrez 4950420
GI 134292912
INSDC ABO57183.1
NCBI Locus Tag BCEP1808_RS21020
NCBI Old Locus Tag Bcep1808_4203
RefSeq WP_011881535.1
UniParc UPI00003A5281
UniProtKB Acc A4JLN0
UniProtKB ID A4JLN0_BURVG
UniRef100 UniRef100_A4JLN0
UniRef50 UniRef50_Q2T7V4
UniRef90 UniRef90_A0A095E814

Product

Feature Type CDS
Coding Frame 1
Product Name
BceD
Product Name Confidence: Class 1
Product Name Confidence: Class 2
Synonyms protein tyrosine phosphatase
phosphotyrosine phosphatase BceD
Evidence for Translation
Charge (pH 7) 4.34
Kyte-Doolittle Hydrophobicity Value -0.316
Molecular Weight (kDa) 16321.5
Isoelectric Point (pI) 8.92

Subcellular localization

Individual Mappings
Localization Confidence PMID
Cytoplasmic Class 3
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 279 genera

Orthologs/Comparative Genomics

Burkholderia Ortholog Group BG004849 (632 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: Bcep1808_4203
Search term: bceD
Search term: BceD

Human Homologs

References

Functional analysis of Burkholderia cepacia genes bceD and bceF, encoding a phosphotyrosine phosphatase and a tyrosine autokinase, respectively: role in exopolysaccharide biosynthesis and biofilm formation.
Ferreira AS, Leitão JH, Sousa SA, Cosme AM, Sá-Correia I, Moreira LM
Appl Environ Microbiol 2007 Jan;73(2):524-34
PubMed ID: 17114319
Distribution of cepacian biosynthesis genes among environmental and clinical Burkholderia strains and role of cepacian exopolysaccharide in resistance to stress conditions.
Ferreira AS, Leitão JH, Silva IN, Pinheiro PF, Sousa SA, Ramos CG, Moreira LM
Appl Environ Microbiol 2010 Jan;76(2):441-50
PubMed ID: 19948863