Burkholderia pseudomallei K96243, BPSS1997 (oxa)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
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Gene Feature Overview

Strain Burkholderia pseudomallei K96243 - Assembly GCF_000011545.1
GCF_000011545.1|latest
Locus Tag
BPSS1997
Name
oxa
Replicon chromosome 2
Genomic location 2701464 - 2702273 (- strand)

Cross-References

RefSeq YP_112003.1
GI 53723018
Entrez 3095413
GI 53723018
INSDC CAH39475.1
NCBI Locus Tag BPSS1997
RefSeq YP_112003.1,GeneID
UniParc UPI0000350846
UniProtKB Acc H7C757
UniProtKB ID H7C757_BURPS
UniRef100 UniRef100_Q6ZZU6
UniRef50 UniRef50_Q6ZZU6
UniRef90 UniRef90_Q6ZZU6

Product

Feature Type CDS
Coding Frame 1
Product Name
beta-lactamase precursor
Synonyms
Evidence for Translation
Charge (pH 7) 9.34
Kyte-Doolittle Hydrophobicity Value -0.200
Molecular Weight (kDa) 29495.4
Isoelectric Point (pI) 9.86

Subcellular localization

Individual Mappings
Localization Confidence PMID
Unknown Class 3
Additional evidence for subcellular localization

AMR gene predictions from CARD database

Identified using the Resistance Gene Identifier (RGI)

Model Name Definition Accession Model Type (?) SNP Cutoff Bit Score Percent Identity CARD Version
OXA-59 OXA-59 is a beta-lactamase found in Burkholderia pseudomallei ARO:3001772 protein homolog model Perfect 0.0 100.0 1.2.1

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

PDB 3D Structures

Accession Header Accession Date Compound Source Resolution Method Percent Identity
6NI0 HYDROLASE 12/25/18 Crystal Structure of the Beta Lactamase Class D YbxI from Burkholderia thailandensis BURKHOLDERIA THAILANDENSIS 2.3 X-RAY DIFFRACTION 91.2

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 90 genera

Orthologs/Comparative Genomics

Burkholderia Ortholog Group BG006349 (508 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: BPSS1997
Search term: oxa

Human Homologs

References

No references are associated with this feature.