Strain |
Burkholderia pseudomallei K96243 - Assembly GCF_000011545.1
GCF_000011545.1|latest |
Locus Tag |
BPSS1511
|
Name |
tssM-5
|
Replicon | chromosome 2 |
Genomic location | 2060710 - 2064669 (+ strand) |
Comment | Gene is part of a cluster known as the type VI secretion system gene cluster tss-5 used in much of the early P. pseudomallei literature (PMID:17660433) but later referred to as T6SS-1 cluster later (PMID:21670170, PMID:22007185) and by the B. mallei literature (PMID:22892068, PMID:17555434). |
RefSeq | YP_111518.1 |
GI | 53722533 |
Entrez | 3096208 |
GI | 53722533 |
NCBI Locus Tag | BPSS1511 |
RefSeq | YP_111518.1,GeneID |
UniProtKB Acc | Q63K54 |
UniProtKB ID | Q63K54_BURPS |
Feature Type | CDS |
Coding Frame | 1 |
Product Name |
type VI secretion system protein TssM-5
|
Synonyms |
hypothetical protein |
Evidence for Translation | |
Charge (pH 7) | 23.62 |
Kyte-Doolittle Hydrophobicity Value | -0.183 |
Molecular Weight (kDa) | 142834.0 |
Isoelectric Point (pI) | 9.81 |
Individual Mappings | |
Additional evidence for subcellular localization |
Source 1 | |
Database | VFDB : VF0429 |
Category | T6SS-1 |
Evidence |
ECO:0000314
direct assay evidence used in manual assertion
|
Host Organism | |
Notes | |
Reference | 17984080 |
Results |
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 96 genera
|
Burkholderia Ortholog Group |
BG019347 (316 members) |
Putative Inparalogs | None Found |
STRING database | Search for predicted protein-protein interactions using:
Search term: BPSS1511
Search term: tssM-5
Search term: type VI secretion system protein TssM-5
|
In vivo expression technology identifies a type VI secretion system locus in Burkholderia pseudomallei that is induced upon invasion of macrophages.
Shalom G, Shaw JG, Thomas MS
Microbiology 2007 Aug;153(Pt 8):2689-2699
PubMed ID: 17660433
|
Strategies for Intracellular Survival of Burkholderia pseudomallei.
Allwood EM, Devenish RJ, Prescott M, Adler B, Boyce JD
Front Microbiol 2011;2:170
PubMed ID: 22007185
|
Type VI secretion is a major virulence determinant in Burkholderia mallei.
Schell MA, Ulrich RL, Ribot WJ, Brueggemann EE, Hines HB, Chen D, Lipscomb L, Kim HS, Mrázek J, Nierman WC, Deshazer D
Mol Microbiol 2007 Jun;64(6):1466-85
PubMed ID: 17555434
|