Burkholderia pseudomallei K96243, BPSS0241 (bhuU)

Gene Feature Overview

Strain	Burkholderia pseudomallei K96243 - Assembly GCF_000011545.1 GCF_000011545.1|latest
Locus Tag	BPSS0241
Name	bhuU
Replicon	chromosome 2
Genomic location	327285 - 328406 (- strand)

Cross-References

RefSeq	YP_110260.1
GI	53721275
Entrez	3096191
GI	53721275
INSDC	CAH37687.1
NCBI Locus Tag	BPSS0241
RefSeq	YP_110260.1,GeneID
UniParc	UPI000043B83F
UniProtKB Acc	Q63NQ9
UniProtKB ID	Q63NQ9_BURPS
UniRef100	UniRef100_Q3JHL9
UniRef50	UniRef50_A1UWS5
UniRef90	UniRef90_A1UWS5

Product

Feature Type	CDS
Coding Frame	1
Product Name	BhuU Product Name Confidence: Class 2
Synonyms	hemin ABC transporter membrane protein
Evidence for Translation
Charge (pH 7)	21.76
Kyte-Doolittle Hydrophobicity Value	0.914
Molecular Weight (kDa)	37558.1
Isoelectric Point (pI)	12.10

Subcellular localization

Individual Mappings	Localization Confidence PMID Cytoplasmic Membrane Class 3 20472543
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

Pathogen Association Analysis

Results

Common Found in both pathogen and nonpathogenic strains Hits to this gene were found in 552 genera

Orthologs/Comparative Genomics

Burkholderia Ortholog Group	BG004245 (593 members)
Putative Inparalogs	None Found

Interactions

STRING database

Search for predicted protein-protein interactions using: Search term: BPSS0241 Search term: bhuU Search term: BhuU

Human Homologs

References

In vivo expression technology identifies a type VI secretion system locus in Burkholderia pseudomallei that is induced upon invasion of macrophages. Shalom G, Shaw JG, Thomas MS Microbiology 2007 Aug;153(Pt 8):2689-2699 PubMed ID: 17660433