Burkholderia cenocepacia K56-2Valvano, BURCENK562V_RS26530 (sodC)

Cytoplasmic Membrane
Outer Membrane

Gene Feature Overview

Strain Burkholderia cenocepacia K56-2Valvano
Locus Tag
NCBI Old Locus TagBURCENK562V_C6283
Replicon ctg7180000002941
Genomic location 104128 - 104664 (+ strand)


RefSeq WP_006493653.1
GI 493539770
EC Number
GI 493539770
NCBI Locus Tag BURCENK562V_RS26530
NCBI Old Locus Tag BURCENK562V_C6283
RefSeq WP_006493653.1


Feature Type CDS
Coding Frame 1
Product Name
superoxide dismutase SodC
Product Name Confidence: Class 1
Synonyms superoxide dismutase
Evidence for Translation
Charge (pH 7) 3.82
Kyte-Doolittle Hydrophobicity Value -0.088
Molecular Weight (kDa) 18124.1
Isoelectric Point (pI) 8.54

Subcellular localization

Individual Mappings
Localization Confidence PMID
Periplasmic Class 3
Periplasmic Class 1
Western blot evidence used in manual assertion
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Virulence Evidence

Source 1
Database BGD
Category Response to superoxide
Evidence ECO:0000315
mutant phenotype evidence used in manual assertion
Host Organism Mus musculus
Notes sodC mutation attenuated for virulence in RAW 264.7 macrophages
Reference 17325048

Orthologs/Comparative Genomics

Burkholderia Ortholog Group BG002305 (654 members)
Putative Inparalogs None Found


STRING database Search for predicted protein-protein interactions using:
Search term: sodC

Human Homologs

Ensembl 97, assembly GRCh38.p12
superoxide dismutase 1 [Source:HGNC Symbol;Acc:HGNC:11179]
E-value: 1.4e-05
Percent Identity: 34.8


Characterization of SodC, a periplasmic superoxide dismutase from Burkholderia cenocepacia.
Keith KE, Valvano MA
Infect Immun 2007 May;75(5):2451-60
PubMed ID: 17325048