Burkholderia cenocepacia K56-2Valvano, BURCENK562V_RS32670 (aidA)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown

Gene Feature Overview

Strain Burkholderia cenocepacia K56-2Valvano
GCF_000333155.2|latest
Locus Tag
BURCENK562V_RS32670
NCBI Old Locus TagBURCENK562V_C7254
Name
aidA
Replicon ctg7180000002943
Genomic location 375795 - 376298 (+ strand)

Cross-References

RefSeq WP_006483191.1
GI 493529175
GI 493529175
NCBI Locus Tag BURCENK562V_RS32670
NCBI Old Locus Tag BURCENK562V_C7254
RefSeq WP_006483191.1

Product

Feature Type CDS
Coding Frame 1
Product Name
nematocidal protein AidA
Product Name Confidence: Class 1
Synonyms inclusion body protein
Evidence for Translation
Charge (pH 7) -0.66
Kyte-Doolittle Hydrophobicity Value -0.266
Molecular Weight (kDa) 18871.3
Isoelectric Point (pI) 6.50

Subcellular localization

Individual Mappings
Localization Confidence PMID
Cytoplasmic Class 3
Unknown Class 3
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Virulence Evidence

Source 1
Database BGD
Category AidA
Evidence ECO:0000315
mutant phenotype evidence used in manual assertion
Host Organism Caenorhabditis elegans
Notes aidA mutant attenuated for slow killing of Caenorhabditis elegans
Reference 15557647

Orthologs/Comparative Genomics

Burkholderia Ortholog Group BG004444 (417 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: aidA

Human Homologs

References

Identification of a novel virulence factor in Burkholderia cenocepacia H111 required for efficient slow killing of Caenorhabditis elegans.
Huber B, Feldmann F, Köthe M, Vandamme P, Wopperer J, Riedel K, Eberl L
Infect Immun 2004 Dec;72(12):7220-30
PubMed ID: 15557647