Burkholderia cenocepacia J2315, BCAM2166 (penR)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse

Gene Feature Overview

Strain Burkholderia cenocepacia J2315
GCF_000009485.1|latest
Locus Tag
BCAM2166
NCBI Locus TagQU43_RS65195
Name
penR
Replicon chromosome 2
Genomic location 2414157 - 2415047 (+ strand)

Cross-References

RefSeq WP_006491626.1
GI 206564003
Entrez 6930596
GI 206564003
INSDC CAR56024.1
NCBI Locus Tag QU43_RS65195
NCBI Old Locus Tag BCAM2166
RefSeq WP_006491626.1,GeneID
UniParc UPI00017B9F54
UniProtKB Acc B4EFW3
UniProtKB ID B4EFW3_BURCJ
UniRef100 UniRef100_B4EFW3
UniRef50 UniRef50_P24734
UniRef90 UniRef90_B4EFW3

Product

Feature Type CDS
Coding Frame 1
Product Name
LysR family regulatory protein
Synonyms
Evidence for Translation
Charge (pH 7) 0.88
Kyte-Doolittle Hydrophobicity Value -0.002
Molecular Weight (kDa) 32688.3
Isoelectric Point (pI) 7.52

Subcellular localization

Individual Mappings
Localization Confidence PMID
Cytoplasmic Class 3
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 468 genera

Orthologs/Comparative Genomics

Burkholderia Ortholog Group BG003739 (935 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: BCAM2166
Search term: penR

Human Homologs

References

Cell Wall Recycling-Linked Coregulation of AmpC and PenB β-Lactamases through ampD Mutations in Burkholderia cenocepacia.
Hwang J, Kim HS
Antimicrob Agents Chemother 2015 Dec;59(12):7602-10
PubMed ID: 26416862