Burkholderia cenocepacia J2315, BCAM2165 (penB)

Gene Ontology

Ontology	Accession	Term	GO Evidence	Evidence Ontology (ECO) Code	Reference	Comments
Molecular Function	GO:0008800	beta-lactamase activity	ISS Inferred from Sequence or Structural Similarity	ECO:0000044 sequence similarity evidence
Biological Process	GO:0046677	response to antibiotic	ISM Inferred from Sequence Model Term mapped from: InterPro:PR00118	ECO:0000259 match to InterPro signature evidence used in automatic assertion
Biological Process	GO:0030655	beta-lactam antibiotic catabolic process	ISM Inferred from Sequence Model Term mapped from: InterPro:PR00118	ECO:0000259 match to InterPro signature evidence used in automatic assertion
Molecular Function	GO:0008800	beta-lactamase activity	ISM Inferred from Sequence Model Term mapped from: InterPro:PR00118	ECO:0000259 match to InterPro signature evidence used in automatic assertion

Pathways

Database	Xref	Pathway	Version	Evidence	PMID
KEGG (InterPro)	00311	Penicillin and cephalosporin biosynthesis	InterPro 5.36-75.0	ECO:0000259 match to InterPro signature evidence used in automatic assertion
KEGG	bcj01130	Biosynthesis of antibiotics	73.0+/03-31, Mar 15	ECO:0000249 sequence similarity evidence used in automatic assertion
KEGG	bcj00311	Penicillin and cephalosporin biosynthesis	73.0+/03-31, Mar 15	ECO:0000249 sequence similarity evidence used in automatic assertion
KEGG	bcj01501	beta-Lactam resistance	73.0+/03-31, Mar 15	ECO:0000249 sequence similarity evidence used in automatic assertion
KEGG	bcj01110	Biosynthesis of secondary metabolites	73.0+/03-31, Mar 15	ECO:0000249 sequence similarity evidence used in automatic assertion

Functional Predictions from Interpro

Analysis	Accession	Description	Interpro Accession	Interpro Description	Amino Acid Start	Amino Acid Stop	E-value
PRINTS	PR00118	Beta-lactamase class A signature	IPR000871	Beta-lactamase, class-A	244	259	3.4E-75
PRINTS	PR00118	Beta-lactamase class A signature	IPR000871	Beta-lactamase, class-A	191	216	3.4E-75
ProSitePatterns	PS00146	Beta-lactamase class-A active site.	IPR023650	Beta-lactamase, class-A active site	89	104	-
PRINTS	PR00118	Beta-lactamase class A signature	IPR000871	Beta-lactamase, class-A	165	189	3.4E-75
PRINTS	PR00118	Beta-lactamase class A signature	IPR000871	Beta-lactamase, class-A	129	154	3.4E-75
PRINTS	PR00118	Beta-lactamase class A signature	IPR000871	Beta-lactamase, class-A	87	104	3.4E-75
PRINTS	PR00118	Beta-lactamase class A signature	IPR000871	Beta-lactamase, class-A	56	80	3.4E-75
SUPERFAMILY	SSF56601		IPR012338	Beta-lactamase/transpeptidase-like	56	310	1.67E-81
Pfam	PF13354	Beta-lactamase enzyme family			77	284	1.9E-42
PRINTS	PR00118	Beta-lactamase class A signature	IPR000871	Beta-lactamase, class-A	227	242	3.4E-75
ProSiteProfiles	PS51318	Twin arginine translocation (Tat) signal profile.	IPR006311	Twin-arginine translocation pathway, signal sequence	1	33	8.12
Gene3D	G3DSA:3.40.710.10				49	311	2.9E-85

Search for additional functional domains at the NCBI CDD database website. Go to this protein's amino acid sequence and follow the link.