Burkholderia cenocepacia J2315, BCAM0443 (copR)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
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Gene Feature Overview

Strain Burkholderia cenocepacia J2315
GCF_000009485.1|latest
Locus Tag
BCAM0443
NCBI Locus TagQU43_RS56610
Name
copR
Replicon chromosome 2
Genomic location 498585 - 499256 (- strand)

Cross-References

RefSeq WP_006484565.1
GI 206562306
Entrez 6928221
GI 206562306
INSDC CAR54301.1
NCBI Locus Tag QU43_RS56610
NCBI Old Locus Tag BCAM0443
RefSeq WP_006484565.1,GeneID
UniParc UPI00017B9CB3
UniProtKB Acc B4EJG6
UniProtKB ID B4EJG6_BURCJ
UniRef100 UniRef100_B4EJG6
UniRef50 UniRef50_Q39YA3
UniRef90 UniRef90_B4EJG6

Product

Feature Type CDS
Coding Frame 1
Product Name
CopR
Product Name Confidence: Class 2
Synonyms
Evidence for Translation
Charge (pH 7) -4.27
Kyte-Doolittle Hydrophobicity Value -0.109
Molecular Weight (kDa) 25527.1
Isoelectric Point (pI) 5.24

Subcellular localization

Individual Mappings
Localization Confidence PMID
Cytoplasmic Class 3
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 626 genera

Orthologs/Comparative Genomics

Burkholderia Ortholog Group BG004576 (249 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: BCAM0443
Search term: copR
Search term: CopR

Human Homologs

References

Identification of a copper-responsive two-component system on the chromosome of Escherichia coli K-12.
Munson GP, Lam DL, Outten FW, O'Halloran TV
J Bacteriol 2000 Oct;182(20):5864-71
PubMed ID: 11004187