Burkholderia cenocepacia J2315, BCAM0393

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
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Gene Feature Overview

Strain Burkholderia cenocepacia J2315
GCF_000009485.1|latest
Locus Tag
BCAM0393
NCBI Locus TagQU43_RS56345
Name
Replicon chromosome 2
Genomic location 445354 - 446160 (- strand)

Cross-References

RefSeq WP_006485469.1
GI 206562254
Entrez 6928176
GI 206562254
INSDC CAR54249.1
NCBI Locus Tag QU43_RS56345
NCBI Old Locus Tag BCAM0393
RefSeq WP_006485469.1,GeneID
UniParc UPI00017B9C1E
UniProtKB Acc B4EJB4
UniProtKB ID B4EJB4_BURCJ
UniRef100 UniRef100_A0A0D1BK77
UniRef50 UniRef50_G8ZKX1
UniRef90 UniRef90_A0A095F8F4

Product

Feature Type CDS
Coding Frame 1
Product Name
putative beta-lactamase
Product Name Confidence: Class 2
Synonyms
Evidence for Translation
Charge (pH 7) 4.37
Kyte-Doolittle Hydrophobicity Value -0.091
Molecular Weight (kDa) 28782.4
Isoelectric Point (pI) 9.06

Subcellular localization

Individual Mappings
Localization Confidence PMID
Unknown Class 3
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 88 genera

Orthologs/Comparative Genomics

Burkholderia Ortholog Group BG006349 (508 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: BCAM0393

Human Homologs

References

OXA-18, a class D clavulanic acid-inhibited extended-spectrum beta-lactamase from Pseudomonas aeruginosa.
Philippon LN, Naas T, Bouthors AT, Barakett V, Nordmann P
Antimicrob Agents Chemother 1997 Oct;41(10):2188-95
PubMed ID: 9333046
Erratum in: J Bacteriol. 2009 Apr;191(8):2907.
The genome of Burkholderia cenocepacia J2315, an epidemic pathogen of cystic fibrosis patients.
J Bacteriol. 2009 Jan;191(1):261-77.
PubMed ID: 18931103