Burkholderia cenocepacia J2315, BCAM0387 (poxB)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
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Gene Ontology

Ontology Accession Term GO Evidence Evidence Ontology (ECO) Code Reference Comments
Molecular Function GO:0030976 thiamine pyrophosphate binding
ISM
Inferred from Sequence Model
Term mapped from: InterPro:PF00205
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Molecular Function GO:0003824 catalytic activity
ISM
Inferred from Sequence Model
Term mapped from: InterPro:PF02775
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Molecular Function GO:0000287 magnesium ion binding
ISM
Inferred from Sequence Model
Term mapped from: InterPro:PF00205
 ECO:0000259
match to InterPro signature evidence used in automatic assertion

Pathways

Database Xref Pathway Version Evidence PMID
KEGG bcj00620 Pyruvate metabolism 73.0+/03-31, Mar 15 ECO:0000249
sequence similarity evidence used in automatic assertion

Functional Predictions from Interpro

Analysis Accession Description Interpro Accession Interpro Description Amino Acid Start Amino Acid Stop E-value
Gene3D G3DSA:3.40.50.970 1 170 1.8E-54
Gene3D G3DSA:3.40.50.1220 174 328 6.3E-44
SUPERFAMILY SSF52518 IPR029061 Thiamin diphosphate-binding fold 354 553 7.79E-55
SUPERFAMILY SSF52518 IPR029061 Thiamin diphosphate-binding fold 2 172 1.77E-42
Pfam PF02775 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain IPR011766 Thiamine pyrophosphate enzyme, C-terminal TPP-binding 376 522 5.8E-36
Pfam PF00205 Thiamine pyrophosphate enzyme, central domain IPR012000 Thiamine pyrophosphate enzyme, central domain 186 314 2.4E-28
CDD cd07039 TPP_PYR_POX 2 160 4.67647E-75
CDD cd02014 TPP_POX 354 530 1.18649E-88
Pfam PF02776 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain IPR012001 Thiamine pyrophosphate enzyme, N-terminal TPP-binding domain 2 162 2.0E-39
ProSitePatterns PS00187 Thiamine pyrophosphate enzymes signature. IPR000399 TPP-binding enzyme, conserved site 413 432 -
Gene3D G3DSA:3.40.50.970 345 568 2.4E-61
SUPERFAMILY SSF52467 IPR029035 DHS-like NAD/FAD-binding domain superfamily 177 343 2.45E-40

Search for additional functional domains at the NCBI CDD database website. Go to this protein's amino acid sequence and follow the link.